CPAP对小儿重症肺炎的疗效及安全性观察

胡明贤

（安康市中心医院儿科，陕西 安康，725000）

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摘要：

目的 探讨鼻塞式持续气道正压通气（CPAP）治疗小儿重症肺炎的疗效与安全性。方法 选择2014年6月至2016年3月本院收治的86例小儿重症肺炎患儿作为研究对象，随机分为对照组和观察组，各43例。观察组采用CPAP给氧治疗，对照组采用面罩式给氧治疗，比较两组临床疗效、临床症状、血气分析指标和不良反应。结果 观察组总有效率（97.67%）显著高于对照组（79.07%），观察组患儿的不良反应发生率（11.63%）显著低于对照组的（23.26%），组间差异均具有统计学意义（P<0.05）。氧疗12、24、36 h后，观察组患儿的PaO2、SaO2显著高于对照组的（P<0.05），PaCO2显著低于对照组的（P<0.05）。结论 小儿重 症肺炎应用CPAP治疗临床疗效可靠，不良反应风险较低。

关键词：小儿；重症肺炎；鼻塞式持续气道正压通气

中图分类号：R725.6 文献标志码：A文章编号：2096-1413(2017)11-0097-02

Effect and safety observation of CPAP on children with severe pneumonia
HU Ming-xian
(Department of Pediatrics, Ankang Central Hospital, Ankang 725000, China)

ABSTRACT: Objective To investigate the effect and safety of nasal continuous positive airway pressure (CPAP) in children with severe pneumonia. Methods Eight -six cases of children with severe pneumonia in our hospital from June 2014 to March 2016 were selected as the research objects, which were randomly divided into control group and observation group, with 43 cases in each group. The observation group was treated with CPAP, while the control group was treated with face mask oxygen therapy. The clinical effect, clinical symptoms, blood gas analysis and adverse reaction of the two groups were compared. Results The total effective rate of the observation group was 97.67%, which was significantly higher than 79.07% of the control group (P<0.05). The incidence rate of adverse reaction of the observation group was 11.63%, which was significantly lower than 23.26% of the control group (P<0.05). After 12, 24 and 36 hour treatment, the PaO2 and SaO2 of the observation group were significantly higher than those of the control group (P <0.05), and the PaCO2 was significantly lower than that of the control group (P<0.05). Conclusion Clinical effect of CPAP treatment in children with severe pneumonia is reliable, and the risk of adverse reaction is low.
KEYWORDS: pediatric; severe pneumonia; nasal continuous positive airway pressure (CPAP)

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