临床 I期成人型卵巢颗粒细胞瘤 31例临床分析

刘华梅

襄阳市东风人民医院妇产科，湖北 襄阳，441004

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摘要：

目的 探讨临床 I期成人型卵巢颗粒细胞瘤（GCTO）的临床特点及治疗方法。方法 回顾性分析临床 I期成人型卵巢颗粒细胞瘤的病例资料，比较不同手术方式及是否化疗对预后的影响。结果 本组患者 31例，三种手术方式比较，患者 5年生存率及 10年生存率均无显著性差异（P＞0.05）。化疗与未化疗患者 5年生存率及 10年生存率均无显著性差异（P＜0.05）。结论 对于年龄小、有生育要求的 I期成人型卵巢颗粒细胞瘤患者，在对侧卵巢无异常、腹腔冲洗液肿瘤细胞检查阴性的前提下，可考虑行单侧附件切除术；对于年龄大，无生育要求或围绝经和绝经后的玉期成人型卵巢颗粒细胞瘤患者，则行全子宫切除并双侧附件切除术，必要时大网膜切除。若无高危因素（术前肿瘤破裂或分化差），术后有密切随访条件，一般不需化疗。

关键词：临床 I期成人型卵巢颗粒细胞瘤；存活率；预后

中图分类号：R737.3 文献标志码：A文章编号：2096-1413(2018)07-0079-02

Clinical Analysis of 30 cases of clinicalI-stage adultgranulosa
celltum orofovary



LIU Hua-mei
(Gynaecology and Obstetrics Department, Xiangyang Dongfeng People`s Hospital, Xiangyang 441004,China)


ABSTRACT: Objective To explore the clinical characteristics and treatment of clinicalI-stage adult granulosa cell tumor ofovary (GCTO).Methods The effects of differents urgical methods and chemo therapy on prognosis were compared by retrospective an alysis of the clinical data of clinicalI-stage adult GCTO. Results There were 31 patients in this group.The sur-vival rate of 5 years and survival rate of 10 years had no statistical significant difference among three types of surgery respectively(P＞0.05). The survival rate of 5 yearsand survivalrate of 10 yearshad no statistical significant difference between chemo therapygroup and non-chemo therapy patients(P＜0.05). Conclusion The young or patients with fertility requirements could considerto unilate raladnexectomy if anotherovary is normal,and the tumorcells are tested negative in periton eallavage fluid. Forolder,childless or post menopausal patients,the total hysterectomy and bilateral adnexectomy are performed and the great omentum resection could considerifitis necessary. Chemotherapy is generally not required if there is no high risk factor (preoperative tumor rupture or poor differentiation) and has closefollow-up condition after surgery.                                                                                                                                                                                                                                                                                                    KEYWORDS: clinicalI-stage adultgranulosa celltumor of ovary; survivalrate; prognosis

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