抗生素与安宫黄体酮联合治疗子宫内膜炎的临床效果

吴锦

（陕西省西安市长安区妇幼保健院，陕西 西安，710100）

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摘要：

目的 探讨抗生素与安宫黄体酮联合治疗子宫内膜炎的临床效果。方法 选取在我院接受治疗的60 例子宫内膜炎患者，随机 分为试验组及对照组，每组30 例，对照组患者给予单纯抗生素治疗，试验组患者给予抗生素与安宫黄体酮联合治疗。对 两组患者的治疗效果进行比较。结果 试验组患者的总有效率为96.7%，明显高于对照组的80.0%（P<0.05）。治疗后，两组患 者的MMP-9、IL-2、IL-4 及IL-10 水平均明显优于治疗前，且试验组明显优于对照组（P<0.05）。试验组患者子宫内膜厚度及 子宫状态恢复时间明显优于对照组（P<0.05）。试验组患者月经恢复正常率明显高于对照组，阴道不规则出血率明显低于对 照组（P<0.05）。结论 抗生素与安宫黄体酮联合治疗子宫内膜炎临床效果显著，安全性较高，可有效促进患者子宫状态恢复，改善月经情况，值得临床推广应用。

 

关键词：抗生素；安宫黄体酮；子宫内膜炎

中图分类号：R711.32文献标志码：A文章编号：2096-1413(2018)01-0080-02

Clinical effect of antibiotics combined with medroxy progesterone in the treatment of endometritis
WU Jin
(Maternal and Child Health Hospital of Chang``an District, Xi``an 710100, China)

ABSTRACT: Objective To investigate the clinical effect of antibiotics combined with medroxy progesterone in the treatment of endometritis. Methods Sixty endometritis patients admitted in our hospital were selected as the study objects. All the patients were randomly divided into experimental group and control group, with 30 cases in each group. The control group received antibiotics treatment, and the experimental group accepted antibiotics combined with medroxy progesterone. The clinical effects of the two groups were compared. Results The total effective rate of the experimental group was 96.7%, which was higher than 80.0% of the control group (P<0.05). After treatment, the levels of MMP-9, IL-2, IL-4 and IL-10 of the two groups were better than those before treatment, and those of the observation group were better than the control group (P<0.05). The endometrium thickness and the recovery time of the uterus in the experimental group were obviously superior to those of the control group (P<0.05). The rate of normal menstruation in the experimental group was significantly higher than that in the control group, and the irregular vaginal bleeding rate was significantly lower than that of the control group (P<0.05). Conclusion Antibiotics combined with medroxy progesterone in the treatment of endometritis has remarkable clinical effect and high safety, it can effectively promote the recovery of the state of the uterus and improve the situation of menstruation, which is worthy of clinical application.
KEYWORDS: antibiotics; medroxy progesterone; endometritis

参考文献：
[1] 周建华.安宫黄体酮联合抗生素治疗子宫内膜炎的效果观察[J].北方药学,2017,14(6):105-106.
[2] 佟建敏.抗生素联合妇科千金片治疗子宫内膜炎的临床疗效观察[J].临床合理用药杂志,2016,9(5):65-66.
[3] 曲凤占.安宫黄体酮联合抗生素治疗子宫内膜炎的效果观察[J].临床合理用药杂志,2016,9(20):65-66.
[4] 任伟茹.安宫黄体酮联合抗生素治疗子宫内膜炎的临床研究[J].中国医学创新,2011,8(3):51-52.
[5] 朱孝琳.甲孕酮联合二联抗生素对子宫内膜炎患者细胞因子的影响及疗效观察[J].实用药物与临床,2013,16(11):1086-1088.
[6] 郭瑛.抗生素联合妇科千金片治疗子宫内膜炎的临床效果分析[J].黑龙江医学,2015,29(3):291-292.