活血化瘀类中药注射剂临床应用分析

齐永红

（陕西省康复医院，陕西 西安，710065）

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摘要：

目的 探讨活血化瘀类中药注射剂的临床应用效果与不良反应发生情况。方法 选择2015年1月至2015年12月在我院使用活血化瘀类中药注射剂的患者140例，记录与观察所有患者的预后情况，调查患者在使用活血化瘀类中药注射剂中出现的不良反应发生情况，并进行危险因素的分析。结果 140例患者经过活血化瘀类中药注射剂治疗后，痊愈98例，好转32例，无效10例，治疗总有效率为92.9%；发生不良反应18例，发生率为12.9%，其中发热4例、恶心呕吐8例，皮疹4例，过敏反应1 例，腹胀1例。经过Logistic回归分析结果显示，患者年龄、注射剂剂量（超量）、合并疾病与体重指数为导致使用活血化瘀类中药注射剂后发生不良反应的主要危险因素（P<0.05）。结论 活血化瘀类中药注射剂具有很好的治疗效果，但同时 也有一定的不良反应，在临床上需要根据危险因素合理应用，促进患者康复。

关键词：活血化瘀类中药注射剂；不良反应；危险因素

中图分类号：R288文献标志码：A文章编号：2096-1413(2017)16-0118-02

Clinical analysis of traditional Chinese medicine injections of promoting blood circulation

and removing blood stasis
QI Yong-hong
(Shaanxi Kangfu Hospital, Xi`an 710065, China)

ABSTRACT: Objective To investigate the clinical application effect and adverse reaction of traditional Chinese medicine injections of promoting blood circulation and removing blood stasis. Methods From January 2015 to December 2015, 140 cases of patients used traditional Chinese medicine injections of promoting blood circulation and removing blood stasis were selected. The prognosis of all the patients were recorded and observed, and the adverse reaction and risk factors of the patients using traditional Chinese medicine injections of promoting blood circulation and removing blood stasis were investigated. Results One hundred and forty cases were treated with traditional Chinese medicine injection of activating blood circulation to dissipate stasis. After treatment, 98 cases were cured, 32 cases were improved, 10 cases were ineffective, and the total effective rate was 92.9%. Adverse reactions occurred in 18 cases, and the incidence rate was 12.9%, including 4 cases of fever, 8 cases of nausea and vomiting, 4 cases of skin rash, 1 case of allergic reaction, 1 case of abdominal distension. Logistic regression analysis showed that the patients` age, dose of injection （excessive）, combined disease and body mass index were the main risk factors of adverse reaction after the use of the traditional Chinese medicine injection of promoting blood circulation and removing blood stasis (P<0.05). Conclusion Traditional Chinese medicine injection of
promoting blood circulation and removing blood stasis has a very good therapeutic effect, but it also has some adverse reactions, it need rational use according to risk factors in clinical practice, which is conducive to the rehabilitation of patients.

KEYWORDS: taditional Chinese medicine injections of promoting blood circulation and removing blood stasis; adverse reactions; risk factors

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