急性心肌梗死并发心房颤动患者应用胺碘酮治疗的临床疗效及安全性研究
孙红周，张万玲，刘霄霄
（陕西省西安市北方医院，陕西西安）
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摘要：
目的 探讨急性心肌梗死合并心房颤动患者使用胺碘酮治疗的临床疗效及安全性。方法 选取2013年5月至2016年5月于我院接受治疗的78例急性心肌梗死合并心房颤动患者为研究对象，将其随机分为对照组和治疗组各39例，对照组患者给予普罗帕酮治疗，治疗组给予胺碘酮，比较两组患者24h内窦性心律恢复情况，30 d内窦性心律维持及不良反应的发生情况。结果 治疗后，治疗组24h内心房颤动在不同时间段转复率、总转复率、心房颤动转复后30d内窦性心律维持率明显高于对照组，差异有统计学意义（P<0.05）; 治疗组不良反应发生率明显低于对照组，差异有统计学意义（P<0.01）。结论 急性心肌梗死合并心房颤动患者使用胺碘酮治疗临床效果显著，值得临床推广应用。
关键词：急性心肌梗死；心房颤动；胺碘酮
中图分类号：R541.7文献标志码：A文章编号：2096-1413(2017)01-0019-02
The clinical value and safety of amiodarone on patients with acute myocardial infarction complicated with atrial fibrillation
SUN Hong-zhou, ZHANG Wan-ling, LIU Xiao-xiao (Xi an North Hospital, Xian 710043, China)
ABSTRACT: Objective To investigate the clinical value of amiodarone on patients with acute myocardial infarction complicated with atrial fibrillation. Methods Seventy -eight cases of acute myocardial infarction complicated with atrial fibrillation patients in our hospital from May 2013 to May 2016 were selected and devided into control group (propafenone) and treatment group (amiodarone), with 39 cases in each group. The recovery of sinus rhythm within 24 h, the maintenance of sinus rhythm and the occurrence of adverse reactions in 30 d were detected and compared. Results The recovery rate of 24 h heart atrial fibrillation and the maintenance rate of sinus rhythm in 30 d in the treatment group were significantly higher than those in the control group, the differences showed statistical significance (P<0.05). The adverse reaction rate in the treatment group was significantly lower than that in the control group (P<0.01). Conclusion Amiodarone in the treatment of patients with acute myocardial infarction complicated with atrial fibrillation has significant clinical value, which is worthy of clinical application.
KEYWORDS: acute myocardial infarction; atrial fibrillation; amiodarone
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