高脂血症与急性胰腺炎的关系及对预后的影响

朱学进

陕西省略阳县人民医院，陕西 汉中，724300

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摘要：

目的 探讨高脂血症（HL）与急性胰腺炎（AP）的关系及对预后的影响。方法 收集急性高脂血症性胰腺炎（AHP）患者 78例，急性胆源性胰腺炎(ABP)患者 50 例，比较二者的血脂水平、并发症发生情况及转归，并根据 BathazarCT 严重指数积分(CTSI)将 AHP 患者分为≤3分（n=25）、4－5分（n=26）、＞6分（n=27），分析 TG 水平与 Balthazar-CTSI评分的相关性。结果 AHP组的 TG、TC 水平明显高于 ABP 组（P<0.05），两组 LDL-C、HDL-C 水平比较，无明显差异（P＞0.05）。TG 水平随着 Balthazar-CTSI评分增加而增加，二者呈正相关（P<0.05）。AHP 组并发症总发生率显著高于 ABP 组（P<0.05），两组死亡率比较，无明显差异（P＞0.05）。结论 HL 尤其是高 TG 密切影响着急性胰腺炎患者的病情程度及转归。

关键词：高脂血症（HL）；急性胰腺炎（AP）；预后

中图分类号：R576；R589.2 文献标志码：A文章编号：2096-1413(2018)09-0048-02

Relationship between hyperlipidemia and acute pancreatitis
and its influence on prognosis


ZHU Xue-jin
(thePeople'sHospitalofLueyangCounty,Hanzhong724300,China)



ABSTRACT: Objective To investigate the relationship between hyperlipidemia (HL) and acute pancreatitis (AP)and its influence on prognosis. Methods Seventy-eight patients with acute hyperlipidemicpancreatitis (AHP)and 50 patients with acute biliary pancreatitis (ABP)were selected. The blood lipid levels,complications and prognosis were compared between the two groups.All the patients were divided into≤ 3 scores group (n=25),4-5 scores group (n=26),＞6 scores group (n=27) according to the score of the Bathazar CT severity index(CTSI).There lationship between TG level and Balthazar-CTSI score was analyzed. Results The levels of TG and TC in the AHP group were significantly higher than those in the ABP group (P<0.05).There was no significant difference between the two groups in the levels of LDL-C and HDL-C (P>0.05). The level of TG increased with the increase of Balthazar-CTSI score,and there was a positive correlation between the two groups(P<0.05).The total incidence of complications in the AHP group were higher than that in the ABP group (P<0.05).There was no significant difference in mortality between the two groups (P>0.05). Conclusion Hyperlipidemia, especially high TG,closely influences the severity and prognosis of patients with acute pancreatitis.
KEYWORDS: hyperlipidemia(HL);acute pancreatitis(AP); prognosis
 

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