门冬氨酸鸟氨酸与多烯磷脂酰胆碱治疗失代偿期 肝硬化的效果

姚佳

西安市蓝田县医院，陕西 西安，710500

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摘要：

目的 研究门冬氨酸鸟氨酸与多烯磷脂酰胆碱治疗失代偿期肝硬化的临床疗效。方法 选取我院 2014年 10月至 2016年 7月收治的肝硬化失代偿期患者 102例为研究对象，随机分为观察组和对照组，各 51例。两组患者均给予常规治疗；在此基础上，观察组采用冬门氨酸鸟氨酸，对照组采用多烯磷脂酰胆碱。比较两组患者的临床效果。结果 观察组的治疗总有效率为 94.12% ，明显高于对照组的 80.39%（P<0.05）；治疗后，两组 TBIL、AST、ALT、PTA、PCⅢ及 C-Ⅳ水平明显优于治疗前，且观察组明显优于对照组（P<0.05）。结论 门冬氨酸鸟氨酸治疗失代偿期肝硬化临床疗效显著，安全性高，值得临床推广。

关键词： 门冬氨酸鸟氨酸；多烯磷脂酰胆碱；代偿期肝硬化

中图分类号：R575.2文献标志码：A文章编号：2096-1413(2018)09-0040-02

Clinical effect of ornithine aspartate and polyenoic phosphatidylcholine
in the treatment of decompensatory cirrhosis
 

YAO Jia
(theHospitalofLantian County,Xi````an 710500,China)




ABSTRACT: Objective To study the clinical efficacy of ornithine aspartate and polyenoic phosphatidylcholine in the treatment of decompensatory cirrhosis.  Methods A total of 102 decompensatory cirrhosis patients admitted in our hospital from October 2014 to July 2016 were selected and randomly divided into observation group and control group,with 51 cases in each group.All the patients were treated with routine treatment; based on routine treatment,the observation group received polyenoic phosphatidylcholine, and the control group accepted ornithineaspartate.The clinical effects of the two groups were compared. Results The total effective rate of treatment in the observation group was 94.12% ,which was significantly higher than 80.39% of the control group (P<0.05). After treatment,the levels of total bilirubin (TBIL),alanine aminotransferase(ALT),aspartate aminotransferase(AST),procollagenⅢ (PCⅢ)and collagenⅣ (C-Ⅳof the two groups were better than those before treatment,and those of the observation group were better than the control group (P<0.05).Conclusion Ornithine aspartate has remarkable clinical effects and high safety in the treatment of decompensatory cirrhosis,wihich is worthy of clinical promotion.
KEYWORDS: aspartate ornithine; polyene phosphatidylcholine; decompensatory cirrhosis

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