液基细胞学检查在宫颈癌筛查中的应用进展

唐利敏，叶元

桂林医学院，广西 桂林，541000

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摘要：

宫颈癌（cervicalcancer）在我国的发病率及死亡率仍处于较高水平，故提高宫颈癌的筛查效率显得尤为重要。液基细胞学（liquid-basedcytology,LBC）技术已经成为宫颈癌的一线筛查手段，本文就近年液基细胞学检测在宫颈癌筛查中的应用进展做一综述。

关键词： 液基细胞学；宫颈癌；筛查

中图分类号： R737.3 文献标志码：A文章编号： 2096-1413(2018)07-0189-02

Application progress of liquid-based cytology in screening for cervical cancer


TANG Li-min,YE Yuan *
(Guilin Medical University, Guilin 541000,China)


ABSTRACT: The incidence and mortality of cervical cancer still hasa high level in China.Therefore, it is crucial to improve the efficiency ofthe cervical cancer screening. Liquid-based cytology has become a first-line screening method around the world. This pape reviews the application progress of LBC in the screening of cervical cancer.

参考文献：
[1]CAMPOS N G,SHARM A M,CLARK A,etal.Resources required forcervicalcancer prevention in low-and middle-income countries[J].PLoS One,2016,11(10):e0164000.
[2] PEIRSON L,FITAPATRCK -LEW IS D,CILISKA D,et al.Screeningfor cervical cancer:a systematic review and meta-analysis[J].SystRev,2013,2(1):1-14.
[3] 黄恩杰 , 罗新 . 中国大陆宫颈细胞学筛查技术实施的现状及缺憾[J]. 中国计划生育和妇产科 ,2016,8(9):4-7.
[4] PAPANICOLAOU GN,TRAUT HF.The diagnostic value of vaginalsmears in carcinoma of the uterus.1941.[J].Arch Pathol Lab Med,1997,121(3):211-224.
[5]PAPANICOLAOU GN.Atlasofexfoliative cytology[M]//Atlasofexfoliative cytology/.Published for the Commonwealth Fund by HarvardUniversityPress,1954:872-872.
[6] HAKAMA M.Screening for cancer of the uterine cervix.From theIARC W orking Group on CervicalCancerScreening and the UICCProjectGroup on the Evaluation ofScreening Programmes for Cancer[J].IARC SciPubl,1986,61(76):1-315.
[7]CHANKONG T,THEERA-UMPON N,AUEPHANW IRIYAKUL S,etal.Automatic cervical cell segmentation and classification in Papsmears[J].ComputMeth ProgBio,2014,113(2):539-556.
[8]BORA K,CHOW DHURY M,M AHANTA LB,etal.Automated classifi-cation ofPap smear images to detectcervicaldysplasia[J].ComputMeth ProgBio,2017,(138):31-47.
[9]SOLOMON D,DAVERY D,KURMAN R,etal.The 2001 bethesda system:terminology forreporting results ofcervicalcytology[J].JAMA-JAM MED ASSOC,2002,287(16):2114-2119.
[10]NAYAR R,W ILUR DC.The bethesda system forreporting cervicalcytology:definitions,criteria,and explanatory notes[J].3rd ed.Berlin:Springer,2015.
[11]RANA S,HODA MD,FIA C,etal.Gynecologic cytology on conventional and liquid-based preparations: a comprehensive review ofsimilaritiesand differences[J].Diagn Cytopathol,2013,41(3):257-278.
[12]SUN XF,GU YQ,W ANG AC,etal.Value assessmentofhigh-riskHPV testand TCT in the screening ofcervicalcarcinoma[J].Chin JExp Clin Virol,2013,27(4):273-276.
[13]SPIYDA LB,W HITAKER KM,M ESSERSMITH A,etal.Clinicalutility ofmolecularbiomarkersin cervicalsquamousintraepitheliallesions in a young adultpopulation[J].J Low GenitTractDi,2016,20(1):26-30.
[14] 师晓艳 , 雷侠 . 宫颈液基细胞学检查与高危型 HPV 检测用于宫颈癌前病变并发感染早期筛查的对比研究 [J]. 中国性科学 ,2017,26(1):33-35.
[15] 王晗 , 高薇炜 , 朱武 , 等 . 薄层液基细胞学检查 ,HPV-DNA 检查联合阴道镜在宫颈癌诊断中的应用价值分析 [J]. 中国微生态学杂志 ,2016,28(11):1330-1332.
[16] 杨淑丽 , 段微 , 苗劲蔚 , 等 . 阴道残端细胞学异常病例 107 例临床分析 [J]. 中国医刊 ,2013,48(8):73-75.
[17]LARSON DM,COPELAND LJ,STRINGER CA,etal.Recurrentcer原vicalcarcinomaafterradicalhysterectomy[J].GynecolOncol,1988,30(3):381-387.