更年强骨汤治疗更年期骨质疏松症的临床效果

刘亚梅 1 ,刘建梅 2* ,刘宇 3

1.延安市人民医院，陕西 延安，716000；2.延安市宝塔区南泥湾中心卫生院,陕西 延安,716000； 3.延安市七里铺柳林社区卫生服务中心，陕西 延安，716000

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摘要：

目的 探讨更年强骨汤治疗更年期骨质疏松症的临床效果。方法 将我院 94例更年期骨质疏松症患者随机分为观察组与对照组,每组 47例。对照组患者给予尼尔雌醇片治疗，观察组患者给予更年强骨汤联合尼尔雌醇片治疗。比较两组患者的临床效果。结果 观察组总有效率为 93.62% ，明显高于对照组的 78.72%（P＜0.05）；治疗后，两组患者的骨密度、血钙、E2 及FSH 水平明显优于治疗前，且观察组明显优于对照组（P＜0.05）；两组患者服药期间均未发生不良反应。结论 更年强骨汤联合常规西药治疗更年期骨质疏松症疗效显著，可有效改善患者内分泌，提高骨密度及血钙水平，具有较好的临床应用价值。

关键词： 更年强骨汤；更年期骨质疏松症；尼尔雌醇片

中图分类号：R259文献标志码：A文章编号： 2096-1413(2018)07-0116-02

Clinical effect of Gengnian Qianggu decoction in the treatment
of climacteric osteoporosis


LIU Ya-mei 1 ,LIU Jian-mei 2* ,LIU Yu 3
(1.Yan`an People`sHospital,Yan`an 716000; 2.Nanniwan Central Health Center of Baota District,Yan`an 716000;
3.Liulin CommunityHealth ServiceCenterin Qilipu,Yan``an 716000,China)



ABSTRACT: Objective To investigate the clinical effect of Gengnian Qianggu decoction in the treatment of climacteric osteoporosis. Methods Ninety-four climacteric osteoporosis were selected and randomly divided into observation group and controlgroup,with 47 cases in each group.The controlgroup wasgiven nierestrol tablet,and the observation group was treated with Gengnian Qianggu decoction combined with nierestroltablet.The clinical effects of the two groups were compared. Results The total effective rate of the observation group was 93.62% ,which was higher than 78.72% ofthe control group(P<0.05). After treatment, the levels of bonemineral density, serum calcium, E2 andFSH in the two groups were better than those before treatment, and those of the observation group were better than the control group (P<0.05). There were no adverse reactions occurred in the two groups during the period of take medicine.Conclusion Gengnian Qianggu decoctio combined with routine western medicine in the treatment of climacteric osteoporosis hasre markable clinical effects. It can effectively improve the endocrine, bone mineral density and serum calcium level,which has good clinical application value.                                   

KEYWORDS: Gengnian Qianggu decoction; climacteric osteoporosis; nierestrol tablet


参考文献：
[1] 金桥 , 牛志军 . 补肾活血汤联合钙尔奇治疗绝经后原发性骨质疏松症疗效观察 [J]. 四川中医 ,2015,33(6):128-130.
[2] 张小勤 , 谢燕雯 . 密固达对绝经期冠心病合并骨质疏松患者治疗的护理 [J]. 临床医学研究与实践 ,2016,1(15):177.
[3] 曹泽毅 . 中华妇产科学 [M]. 北京 : 人民卫生出版社 ,1999:2285-2287.
[4] 郑筱萸 . 中药新药临床研究指导原则 ( 试行 )[M]. 北京 : 中国医药出版社 ,2002:388耀390.
[5] 冯云波 , 刘小坡 , 曹国龙 , 等 . 淫羊藿总黄酮对骨质疏松大鼠的保护作用 [J]. 中国临床药理学杂志 ,2016,32(15):1425-1427.
[6] 李艳 , 于涛 , 苗明三 . 淫羊藿的化学、药理与临床应用分析 [J]. 中医学报 ,2017,32(4):619-622.