生脉注射液配合常规治疗AMI 后心源性休克的疗效及对心功能、血清cTnI、cTnI-mRNA、CaM和尿量的影响

宋程洁

（甘泉县人民医院，陕西 延安，716100）

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摘要：

目的 探讨生脉注射液配合常规治疗改善AMI 后心源性休克的疗效及对心功能、血清cTnI、cTnI-mRNA、CaM 和尿 量的影响。方法 选择我院收治的AMI 后心源性休克患者120 例，随机分为观察组和对照组，各60 例。对照组予以常规治 疗，观察组在对照组的基础上予以生脉注射液。比较两组临床治疗效果，心功能指标（SBP、LVEF、CI、PCWP），以及cTnI、cTnI-mRNA、CaM 和尿量的变化。结果 治疗后，两组患者心功能指标均有所改善，且观察组明显优于对照组（P<0.05）；治 疗后，两组cTnI 、cTnI-mRNA、CaM 水平明显降低，尿量明显升高，且观察组上述指标明显优于对照组（P<0.05）。观察组 治疗总有效率明显高于对照组，差异具有统计学意义（P<0.05）。结论 生脉注射液能明显改善AMI 后心源性休克患者心 功能，降低血心肌蛋白水平，增加尿路，具有明显抗休克作用，可提高患者临床疗效。

关键词：生脉注射液；AMI；心源性休克；心功能

中图分类号：R542.22；R541.64文献标志码：A文章编号：2096-1413(2018)06-0108-03

Effect of Shengmai injection combined with routine treatment on cardiogenic shock after AMI and its influence on cardiac function, serum cTnI, cTnI-mRNA,
CaM and urine volume SONG Cheng-jie
(the People``s Hospital of Ganquan County, Yan``an 716100, China)

ABSTRACT: Objective To explore the effect of Shengmai injection combined with routine treatment on cardiogenic shock after AMI and its effects on cardiac function, serum cTnI, cTnI-mRNA, CaM and urine volume. Methods A total of 120 cases of patients with cardiogenic shock after AMI treated in our hospital were collected and randomly divided into observation group and control group, with 60 cases in each group. The control group was given routine treatment, and the observation group was given Shengmai injection on the basis of the control group. The clinical effects, the cardiac function indexes (SBP, LVEF, CI, PCWP) and cTnI, cTnI-mRNA, CaM, urine volume were compared between the two groups. Results After treatment, the levels of cardiac function indexes of the two groups improved, and those of the observation group were significantly better than the control group (P<0.05). After treatment, the levels of cTnI, cTnI-mRNA and CaM
increased, and urine volume decreased in the two groups, and those of the observation group were significantly better than the control group (P<0.05). The total effective rate in the observation group was significantly higher than that in the control group (P<0.05). Conclusion Shengmai injection can significantly improve the cardiac function, reduce the levels of blood cardiac protein and increase urinary tract in patients with cardiogenic shock after AMI. And it has obvious antishock effect and can improve the clinical efficacy.
KEYWORDS: Shengmai injection; AMI; cardiogenic shock; cardiac function

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