子宫颈环形电切术与冷刀锥切术治疗子宫颈上皮内瘤变的对比分析

杨亚妮，刘祥芳*

（陕西省西安市鄠邑区妇幼保健院妇产科，陕西 西安，710300）

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摘要：

目的 探究子宫颈环形电切术与冷刀锥切术治疗子宫颈上皮内瘤变的临床效果。方法 选择2014 年1 月至2017 年2月我 院收治的子宫颈上皮内瘤变患者88 例，将所有患者按随机数字表法分为对照组与观察组，各44 例。对照组实施子宫颈冷刀 锥切术，观察组实施子宫颈环形电切术。对比两组手术情况、并发症总发生率、复发情况及术后6 个月HPV 转阴率。结果 观 察组患者的术中出血量少于对照组，手术时间、子宫颈愈合时间短于对照组（P<0.05）。本研究中，术后6 个月观察组HPV 转 阴率略高于对照组，复发率略低于对照组，差异无统计学意义（P>0.05）。观察组并发症总发生率显著低于对照组（P<0.05）。结论 与子宫颈冷刀锥切术相比，子宫颈环形电切术治疗子宫颈上皮内瘤变的效果更优，能减少术中出血量，缩短手术时间和宫颈愈合时间，减少并发症发生率。

关键词：子宫颈上皮内瘤变；子宫颈环形电切术；子宫颈冷刀锥切术

中图分类号：R737.33文献标志码：A文章编号：2096-1413(2018)06-0078-02

Comparative analysis of loop electrosurgical excision procedure and cold knife conization in the treatment of cervical intraepithelial neoplasia
YANG Ya-ni, LIU Xiang-fang*
(Obstetrics and Gynecology Department, Maternal and Child Health Care Hospital of Huyi District, Xi``an 710300, China)

ABSTRACT: Objective To investigate the clinical effects of loop electrosurgical excision procedure (LEEP) and cold knife conization (CKC) in the treatment of cervical intraepithelial neoplasia (CIN). Methods A total of 88 CIN patients in our hospital from January 2014 to February 2017 were selected, and divided into two groups by random number table, with 44 cases in each group. The control group was given CKC, while the observation group was given LEEP. The surgery conditions, total incidence of complication, recurrence rate and negative rate of HPV at 6 months after surgery were compared in the two groups. Results The intraoperative blood loss in the observation group was less than that of the control group, and the operation time and the healing time of the cervix were shorter than those in the control group (P<0.05) ; at 6 months after operation, the recurrence rate in the observation group was lower than that in control group, the negative rate of HPV infection in the observation group was higher than that in the control group, but there were no statistical differences (P>0.05); the total incidence of complications in the observation group was lower than that in the control group (P<0.05). Conclusion LEEP in the treatment of CIN is more effective than CKC, it can reduce intraoperative bleeding loss, shorten operation time and cervical healing time, reduce the incidence of complications.
KEYWORDS: cervical intraepithelial neoplasia; loop electrosurgical excision procedure; cold knife conization

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