不同方式治疗舒张压升高为主的原发性高血压的临床疗效

钟运煜1 ，杨明2*

（镇巴县中医院：1.心内科；2.急诊科，陕西 汉中，723600）

浏览次数：85次 下载次数：435次

摘要：

目的 研究不同方式治疗舒张压升高为主的原发性高血压的临床疗效。方法 选取78 例舒张压升高为主的原发性高血 压患者，对其一般资料予以回顾性分析，按照治疗方法将其分为研究组与对照组，各39 例。对照组行硝苯地平缓释片治疗， 研究组行吲达帕胺与氨氯地平联合治疗。比较两组患者的临床疗效。结果 研究组患者的治疗总有效率高于对照组（P<0.05）。 治疗后，两组患者的舒张压、收缩压均降低，且研究组低于对照组（P<0.05）。两组患者的不良反应总发生率比较，无显著 差异（P>0.05）。结论 吲达帕胺与氨氯地平联合治疗舒张压升高为主的原发性高血压的临床效果显著，不良反应发生率低， 用药安全性高，值得推广运用。

关键词：吲达帕胺；氨氯地平；舒张压升高；原发性高血压

中图分类号：R544.1文献标志码：A文章编号：2096-1413(2018)06-0048-02

Clinical efficacy of different ways in treating the primary hypertension of diastolic blood pressure
ZHONG Yun-yu 1, YANG Ming2 *
(1. Cardiology Department; 2. Emergency Department, the Hospital of Zhenba County, Hanzhong 723600, China)

ABSTRACT: Objective To study the clinical effect of different ways in treating the primary hypertension of diastolic blood pressure. Methods Seventy -eight patients with primary hypertension of diastolic blood pressure were selected, and the general data were retrospectively analyzed and divided into study group and control group according to the treatment methods, with 39 cases in each group. The control group was treated with nifedipine, and the study group was treated with indapamide combined with amlodipine. The clinical effects of the two groups were compared. Results The total effective rate of the study group was higher than that of the control group (P<0.05). After treatment, the diastolic blood pressure and systolic blood pressure of both groups decreased, and those of the study group was lower than the control group (P<0.05). The total incidence of adverse reactions between the two groups showed no significant difference (P>0.05). Conclusion The clinical effect of indapamide combined with amlodipine in the treatment of primary hypertension of diastolic blood pressure is significant, with low incidence of adverse reactions and high safety of the drug, and it is worth popularizing.

KEYWORDS: indapamide; amlodipine; diastolic blood pressure; primary hypertension

参考文献：
[1] 胡小李,肖春晖.厄贝沙坦联合左旋氨氯地平或吲达帕胺对原发性高血压患者血压变异性的影响[J].临床心血管病杂志,2013,29(3):233-235.
[2] 何德全.苯磺酸氨氯地平联合吲达帕胺治疗高血压疗效分析[J].中国药物经济学,2013,8(1):214-215.
[3] 丁智晓.小剂量氢氯噻嗪联合左旋氨氯地平治疗老年原发性高血压的临床观察[J].中外医疗,2016,35(17):51-52.
[4] 王艳付.高血压合并冠心病患者应用吲达帕胺联合氨氯地平片治疗的临床疗效分析[J].中外医学研究,2015,13(5):146-147.
[5] 王晓超.氨氯地平联合复方卡托普利治疗原发性高血压的临床效果评价[J].海峡药学,2015,27(1):122-123.
[6] 史斌.氯沙坦钾联合吲达帕胺或马来酸左旋氨氯地平治疗老年高血压的临床疗效对比[J].临床合理用药杂志,2015,8(7C):5-6.