瑞芬太尼复合异丙酚静脉麻醉用于肥胖乳腺癌患者的临床效果

赵运龙

（安康市汉滨区第一医院，陕西 安康，725000）

浏览次数：113次 下载次数：367次

摘要：

目的 探讨瑞芬太尼复合异丙酚静脉麻醉用于肥胖乳腺癌患者的临床效果。方法 将在我院接受手术治疗的80 例乳腺 癌患者按体重分为对照组（常规体重）和观察组（肥胖），每组40 例。所有患者均采用瑞芬太尼复合异丙酚静脉麻醉，比较两 组患者的临床效果。结果 观察组异丙酚使用剂量明显高于对照组（P<0.05）；观察组患者在麻醉诱导后、插管后10 min、插管 后30 min、手术结束时的HR、SpO2 水平明显低于对照组（P<0.05）；观察组术后睁眼时间、自主呼吸恢复时间、拔管时间及手 术时间明显长于对照组（P<0.05）。结论 瑞芬太尼复合异丙酚静脉麻醉用于肥胖乳腺癌患者临床效果较好，能够较好地维持 血气分析各指标水平，但术后苏醒较正常体重者慢，且很快会感到疼痛，需要采用其他镇痛方式控制疼痛。

关键词：肥胖乳腺癌；瑞芬太尼复合异丙酚；静脉麻醉

中图分类号：R614文献标志码：A文章编号：2096-1413(2018)01-0024-02

Clinical effect of remifentanil combined with propofol intravenous anesthesia in obese breast cancer patients
ZHAO Yun-long
(the First Hospital of Hanbin District, Ankang 725000, China)

ABSTRACT: Objective To investigate the clinical effect of remifentanil combined with propofol intravenous anesthesia in obese breast cancer patients. Methods Eighty breast cancer patients who treated with surgery in our hospital were divided into control group (routine weight patients) and observation group (obese patients), with 40 cases in each group. All the patients received remifentanil combined with propofol intravenous anesthesia. The clinical effects of the two groups were compared. Results The dosage of propofol of the observation group was higher than that of the control group (P<0.05). The levels of HR and SPO2 after anesthesia induction, 10 min after intubation, 30 min after intubation and at the end of the operation in the observation group were lower than those in the control group (P<0.05). The eye opening time, spontaneous breathing recovery time, extubation time and operation time of the observation group were longer than those of the control group (P<0.05). Conclusion Remifentanil combined with propofol intravenous anesthesia in obese breast cancer patients has remarkable clinical effect. It can maintain the level of blood gas analysis, but postoperative recovery is slower than patients with normal body weight, patients will soon feel pain, and it is necessary to use other analgesic methods to control pain.
KEYWORDS: obese breast cancer; remifentanil combined with propofol; intravenous anesthesia

参考文献：
[1] 腾清蕾,王永玲,高建芝.瑞芬太尼复合异丙酚静脉麻醉用于肥胖乳腺癌患者的效果观察[J].中国妇幼保健,2012,27(12):1876-1878.
[2] 曾庆锋,朱华斌,陈华.瑞芬太尼复合异丙酚静脉麻醉应用于肥胖 乳腺癌患者根治术的有效性及可控性[J].中国肿瘤临床与康复,2016,16(6):657-659.
[3] 郝雪峰.瑞芬太尼复合异丙酚静脉麻醉在乳腺癌根治术中的应用观察[J].中国医药导刊,2013,15(11):1853-1854.
[4] 李定鲲.瑞芬太尼和芬太尼复合异丙酚用于全身麻醉维持的效果评价[J].中国实用医药,2013,8(35):171-172.
[5] 洪英才,麻伟青.瑞芬太尼和芬太尼复合异丙酚用于全身麻醉维持的效果比较[J].西南国防医药,2010,20(3):285-286.