无创呼吸机联合氧驱动雾化吸入治疗COPD 合并呼吸衰竭的临床效果

仇绪武，刘毅，马强，梁宏岩

（陕西省森林工业职工医院，陕西 西安，710300）

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摘要：

目的 探讨无创呼吸机联合氧驱动雾化吸入治疗COPD 合并呼吸衰竭的临床效果。方法 选择2014 年1 月至2016 年1 月我院收治的100 例COPD 合并呼吸衰竭的患者作为研究对象，随机分为观察组和对照组，各50 例。对照组患者采用常规 雾化吸入治疗，观察组患者采用无创呼吸机联合氧驱动雾化吸入治疗。比较两组患者的临床效果。结果 治疗后，两组患者的 PaCO2、SaO2 及PaO2 水平均优于治疗前，且观察组明显优于对照组（P<0.05）；治疗后，两组患者的HR 及RR 水平均优于治疗 前，且观察组明显优于对照组（P<0.05）；治疗后，观察组患者的FEV1%、FEV1/FVC 及呼吸困难指数明显优于对照组（P<0.05）；两组患者的不良反应发生率比较，差异无统计学意义（P>0.05）。结论 无创呼吸机联合氧驱动雾化吸入治疗COPD 合并呼吸 衰竭的临床疗效显著，且治疗后患者的不良反应发生率较低。

关键词：无创呼吸机；氧驱动雾化吸入；COPD

中图分类号：R563.8；R563.9文献标志码：A文章编号：2096-1413(2018)01-0022-02

Clinical effect of noninvasive ventilator combined with oxygen driven nebulization in the treatment of COPD

complicated with respiratory failure
QIU Xu-wu, LIU Yi, MA Qiang, LIANG Hong-yan
(Shaanxi Sengong Hospital, Xi``an 710300, China)

ABSTRACT: Objective To discuss the clinical curative effect of noninvasive ventilator combined with oxygen driven nebu lization in the treatment of COPD complicated with respiratory failure. Methods A total of 100 patients with COPD and res piratory failure in our hospital from January 2014 to January 2016 were enrolled in this study. All the patients were ran domly divided into observation group and control group, with 50 cases in each group. The control group was treated with conventional aerosol inhalation, while the observation group was treated with noninvasive ventilator combined with oxygen driven atomizing inhalation. The clinical effects of the two groups were compared. Results After treatment, the levels of Pa CO2, SaO2 and PaO2 of the two groups were better than those before treatment, and those of the observation group were bet ter than the control group (P<0.05). After treatment, the levels of HR and RR of the two groups were better than those be fore treatment, and those of the observation group were better than the control group (P<0.05). After treatment, the levels of FEV1%, FEV1/FVC and dyspnea index of the observation group were better than those of the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion The clinical curative effect of noninvasive ventilator combined with oxygen driven nebulization in the treatment of COPD complicat ed with respiratory failure is significant, and the incidence of adverse reactions is low.
KEYWORDS: noninvasive ventilator; oxygen driven nebulization; chronic obstructive pulmonary disease

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