中国学术期刊网络出版总库入编期刊
CNKI中文期刊全文数据库全文收录期刊
中国核心期刊(遴选)数据库全文收录期刊
万方数据——数字化期刊群收录期刊
中文科技期刊数据库全文收录期刊

主管:陕西省卫生健康委员会
主办:西安心身医学研究所
   西安交通大学第一附属医院
国际标准刊号:ISSN2096—1413
国内统一刊号:CN61—1503/R

间苯三酚联合地西泮在产程中的应用效果研究

闫琼琼

(西安市中心医院妇产科,陕西 西安,710003)

浏览次数:164次 下载次数:377次

摘要:

目的 探讨间苯三酚联合地西泮与消旋山莨菪碱联合地西泮应用于产程的临床疗效。方法 选取我院2015年1月至2016年1月进行阴道试产的120例初产妇为研究对象,随机分为研究组及对照组,每组60 例。研究组患者采用间苯三酚 联合地西泮治疗,对照组采用消旋山莨菪碱联合地西泮治疗。观察两组用药后的临床效果。结果 研究组产妇的宫口开全时 间短于对照组,宫颈水肿发生率低于对照组(P<0.05);两组患者的第二产程比较,无显著差异(P>0.05)。研究组产妇的剖宫 产率明显低于对照组(P<0.05);两组产妇的产后2 h 出血量及新生儿窒息率比较,无显著差异(P>0.05)。结论 间苯三酚联合 地西泮应用于产程能减轻宫颈痉挛、水肿,缓解患者焦虑,加速宫口扩张,促进产程进展,且对母婴无明显不良影响,值得产 科临床应用。

关键词:间苯三酚;地西泮;消旋山莨菪碱;产程进展;阴道分娩

中图分类号:R714.3文献标志码:A文章编号:2096-1413(2017)35-0111-02

    Application effect of phloroglucin combined with diazepam in the stage of labor
    YAN Qiong-qiong
    (Gynaecology and Obstetrice Department, Xi``an Central Hospital, Xi``an 710003, China)

    ABSTRACT: Objective To investigate the clinical efficacy of phloroglucin combined with diazepam and raceanisodamine combined with diazepam in the stage of labor. Methods From January 2015 to January 2016, 120 cases of primipara in our hospital for vaginal trial production were selected as the research objects, and randomly divided into study group and control group, with 60 cases in each group. The study group was treated with phloroglucin combined with diazepam, while the control group was treated with raceanisodamine combined with diazepam. The clinical effects in both groups were observed after drug treatment. Results The uterine neck whole opened time in the study group was shorter than that of the control group, cervical edema rate in the study groups was lower than that of the control group (P<0.05); there was no significant difference in the second stage of labor between the two groups (P>0.05). The cesarean section rate in the study group was significantly lower than that of the control group (P <0.05); there were no significant differences in the maternal postpartum 2 h hemorrhage and neonatal asphyxia rate between the two groups (P >0.05). Conclusion Phloroglucin combined with diazepam can reduce cervical spasms and edema, relieve patient``s anxiety, speed up the expansion of miyaguchi, promote labor progress, with no significant adverse effects on mother and child, which is worthy of clinical application in obstetric.
    KEYWORDS: phloroglucin; diazepam; raceanisodamine; labor progress; vaginal production

    参考文献:
    [1] TABASSUM S,AFRIDI B,AMAN Z.Phloroglucinol for acceleration of labour: double blind, randomized controlled trial[J].J Pak Med Assoc,2005, 55(7):270-273.
    [2] 唐景梅,马丽.宫颈封闭配合气囊助产在足月妊娠引产中的研究 [J].中国医药指南,2012,10(23):215-216.
    [3] 王瑞华,顾成敏,魏东红.间苯三酚应用于产程不同时期的效果分 析[J].中国妇幼保健,2012,27(33):5294-5296.
    [4] 吴霞,翟桂荣,黄醒华.潜伏期应用间苯三酚对第一产程的影响[J]. 中华围产医学杂志,2005,8(3):150-153.
    [5] 李健和,易利丹,彭六保,等.间苯三酚的药理作用与临床应用[J].中 国新药与临床杂志,2011,30(7):494-499.
    [6] 黄玉华,熊国平.间苯三酚在阴道分娩中的临床应用[J].中国医药 导刊,2004,6(4):279-280.
    [7] 姚毓筠.间苯三酚在妇产科的应用[J].医学综述,2011,17(14):2170-2172.
    [8] 黎梅.间苯三酚在妇产科的应用及评价[J].临床合理用药杂志,2014,7(5):174-175.
    [9] QUEGUINEUR B,GOYA L,RAMOS S,et al.Phloroglucinol: antioxidant properties and effects on cellular oxidative markers in human HepG2 cell line[J].Food Chem Toxicol,2012,50(8):2886-2893.

上一篇N/A

下一篇左布比卡因与布比卡因腰麻用于剖宫产术的效果比较