孟鲁司特联合雾化吸入治疗儿童支气管哮喘的疗效分析

罗平丽，刘惠芳

（陕西省宝鸡市眉县人民医院，陕西 宝鸡，722300）

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摘要：

目的 探究孟鲁司特联合雾化吸入治疗儿童支气管哮喘的临床疗效。方法 选取支气管哮喘患儿100 例为研究对象，根 据治疗方式分为对照组和试验组，每组50 例。其中对照组给予抗感染、平喘、止咳、布地奈德雾化吸入治疗，试验组则在此基 础上联合孟鲁司特。观察比较两组患儿的疗效、肺功能改善、症状消失时间及不良反应发生情况。结果 试验组患儿的总有效 率为94.00%，明显高于对照组78.00%（P<0.05）。治疗后，两组患儿的FEV1、PEF 及FVC 水平均较治疗前明显改善，且试验组 均显著优于对照组（P<0.05）。试验组患儿症状、体征消失时间均明显短于对照组（P<0.05）。两组患儿的不良反应发生率比 较，差异无统计学意义（P>0.05）。结论 支气管哮喘患儿接受孟鲁司特联合雾化吸入治疗，可以促进其肺功能的改善，缓解其 临床不良症状，有助于其预后，值得临床使用。

关键词：孟鲁司特；雾化吸入；支气管哮喘

中图分类号：R974文献标志码：A文章编号：2096-1413(2017)35-0046-02

Clinical efficacy analysis of montelukast combined with atomization inhalation in the treatment of bronchial

asthma in children
LUO Ping-li, LIU Hui-fang
(People``s Hospital of Mei County, Baoji 722300, China)

ABSTRACT: Objective To explore the clinical efficacy of montelukast combined with atomization inhalation in treatment of bronchial asthma in children. Methods A total of 100 children with bronchial asthma were selected and randomly divided into control group and experimental group according to the treatment method, with 50 cases in each group. The control group was given the treatment of anti-infection, expectoran, anti-tussive and budesonide aerosol inhalation, and the experimental group was given montelukast on this basis. The therapeutic effect, improvement of lung function, the extinction time of symptoms and incidence of adverse reactions were compared in the two groups. Results The total effective rate of experimental group was 94.00%, which was significantly higher than 78.00% of the control group (P<0.05). After treatment, the levels of FEV1, PEF and FVC in the two groups obviously improved, and those in the experimental group were better than the control group (P<0.05). The extinction time of symptoms in the experimental group were shorter than those in the control group (P< 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion Montelukast combined with atomization inhalation in the treatment of bronchial asthma can promote the improvement of lung function, relieve the clinical symptoms, which is conducive to improve the prognosis and worthy of application in clinic.

KEYWORDS: montelukast; atomization inhalation; bronchial asthma

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