腭咽成型术后患者采用右美托咪啶与咪达唑仑镇静的临床效果分析
陈钰铨，陈强
（乌鲁木齐市眼耳鼻喉专科医院，新疆 乌鲁木齐，830002）
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摘要：
目的 分析腭咽成型术后患者采用右美托咪啶与咪达唑仑镇静的临床效果。方法 选取我院收治的腭咽成型术后患者 80例，根据用药不同分为观察组和对照组，各40 例。观察组患者采用右美托咪啶治疗，对照组患者采用咪达唑仑治疗。比较两组患者术后麻醉苏醒1～2 h 的镇静躁动程度评分、心率、平均动脉压及血氧饱和度。结果 观察组患者术后麻醉苏醒1～2 h 的镇静躁动程度评分明显低于对照组，差异具有统计学意义（P<0.05）。手术后，观察组患者的心率及平均动脉压水平明显低 于对照组，差异具有统计学意义（P<0.05）；两组患者的血氧饱和度水平比较，差异无统计学意义（P>0.05）。结论 腭咽成型术 后患者应用右美托咪啶，可以有效降低患者的躁动，值得临床推广应用。
关键词：腭咽成型术后；咪达唑仑；右美托咪啶；镇静；躁动
中图分类号：R614文献标志码：A文章编号：2096-1413(2017)33-0065-02
Clinical effect analysis of dexmedetomidine and midazolam in patients undergoing uvulopalatopharyngoplasty
CHEN Yu-quan, CHEN Qiang
(Urumqi Ent Hospital, Urumqi 830002, China)
ABSTRACT: Objective To analyze the clinical effect of dexmedetomidine and midazolam in patients undergoing uvulopalatopharyngoplasty. Methods Eighty cases of patients undergoing uvulopalatopharyngoplasty in our hospital were selected and divided into observation group and control group according to different medication, with 40 cases in each group. The observation group received dexmedetomidine, and the control group accepted midazolam. The scores of sedation and agitation, heart rate, mean arterial pressure and blood oxygen saturation after 1-2 h of anesthesia were compared between the two groups. Results The score of sedation and agitation after 1-2 h of anesthesia in the observation group was lower than that in the control group, the difference was statistically significant (P<0.05). After operation, the heart rate and mean arterial pressure levels in the observation group were lower than those in the control group, the difference was statistically significant (P<0.05); but there was no significant difference in the blood oxygen saturation level between the two groups (P>0.05). Conclusion Using dexmedetomidine in patients undergoing uvulopalatopharyngoplasty can effectively reduce the restlessness, which is worthy of clinical application and promotion.
KEYWORDS: uvulopalatopharyngoplasty; midazolam; dexmedetomidine; sedation; restlessness
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