醒脑静联合盐酸纳洛酮抢救脑出血伴昏迷患者的临床效果

强忙春，党亚东

（西安航天总医院急诊科，陕西 西安，710100）

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摘要：

目的 探讨醒脑静联合盐酸纳洛酮抢救脑出血伴昏迷患者的临床效果。方法 选取我院2015年1月至2016年6月收治的脑出血伴昏迷患者216例，将其随机分为研究组和对照组，各108例。对照组患者给予基础治疗加盐酸纳洛酮注射液治疗， 研究组患者在此基础上加用醒脑静注射液治疗，观察两组患者的临床疗效及治疗前后的脑血肿量及昏迷时间。结果 研究组患者临床治疗总有效率为96.30%（104/108），高于对照组的86.11%（93/108）（P<0.05）；治疗前，两组患者脑血肿量差异不具有统计学意义（P>0.05），治疗后，两组患者脑血肿量明显下降，研究组患者下降得更为显著（P<0.05）；研究组患者的昏迷时间 为（7.01±2.01）d，短于对照组的（10.34±1.89）d（P<0.05）。结论 醒脑静联合盐酸纳洛酮治疗脑出血伴昏迷患者的临床效果显 著，可推广使用。

关键词：脑出血；昏迷；醒脑静；盐酸纳洛酮

中图分类号：R743.34文献标志码：A文章编号：2096-1413(2016)27-0021-02

The clinical effect of Xingnaojing combined with naloxone hydrochloride in the treatment of cerebral hemorrhage with coma patients
QIANG Mang-chun, DANG Ya-dong
(Department of Emergency, Xi`an Aerospace General Hospital, Xi`an 710100, China)

ABSTRACT: Objective To investigate the clinical effect of Xi ngnaojing combined with naloxone hydrochloride in the treatment of cerebral hemorrhage with coma patients. Methods Two hundred and sixteen cases of cerebral hemorrhage with coma patients admitted in our hospital from January 2015 to June 2016 were selected and randomly divided into study group and control group, with 108 cases in each group. The control group was given basic treatment combined with naloxone hydrochloride injection, while the study group received Xingnaojing injection on the basis of the control group, the clinical efficacy, cerebral hematoma volume before and after treatment and coma time were observed and compared between the two groups. Results The total effective rate of the study group was 96.30% (104/108), which was significantly higher than 86.11% (93/108) of the control group (P<0.05). Before treatment, the difference in cerebral hematoma volume between the two groups had no statistical significance （P>0.05）; after treatment, the cerebral hematoma volume of the two groups both decreased significantly, but the study group decreased more significantly (P<0.05); The coma time of the study group was (7.01±2.01) d, which was significantly shorter than (10.34±1.89) d of the control group (P<0.05). Conclusion The clinical effect of Xingnaojing combined with naloxone hydrochloride in the treatment of cerebral hemorrhage with coma is positive, which can be widely used.
KEYWORDS: cerebral hemorrhage; coma; Xingnaojing; naloxone hydrochloride

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