红花黄色素联合依达拉奉治疗128例急性脑梗死的效果分析

黄忠卫

（江苏省海门市人民医院，江苏 南通，226100）

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摘要：

目的 观察红花黄色素联合依达拉奉治疗脑梗死的效果。方法 选择2014年1月至2016年1月于我院就诊的急性脑梗塞患者256例，按照随机数字法将患者分为研究组和对照组，各128例。对照组在常规治疗的基础上加用依达拉奉治疗，研究组在对照组的基础上加用红花黄色素治疗。观察两组治疗前后的NIHSS评分和炎症因子变化，以及治疗效果。结果 两组治疗前NIHSS评分均无统计学意义（P>0.05）；治疗后两组较治疗前均有降低，且研究组下降程度高于对照组，差异有统计学意 义（P<0.05）。治疗前两组hs-CRP、IL-2、IL-8 和TNF-α 等水平差异无统计学意义（P>0.05），治疗后两组均有明显降低，且研究组比对照组下降更明显，差异有统计学意义（P<0.05）。研究组治疗有效率为95.31%，高于对照组的83.59%，差异有统计学意义（P<0.05）。结论 红花黄色素联合依达拉奉治疗急性脑梗塞治疗效果显著，可改善患者预后，且安全可靠。

关键词：急性脑梗死；红花黄色素；依达拉奉

中图分类号：R743.3文献标志码：A文章编号：2096-1413(2016)27-0006-02

Effect analysis of safflower yellow pigment combined with edaravone in the treatment of 128 cases of acute cerebral infarction
HUANG Zhong-wei
(People`s Hospital of Haimen City, Nantong 226100, China)

ABSTRACT: Objective To observe the effect of safflower yellow pigment combined with edaravone in the treatment of acute cerebral infarction. Methods Two hundred and fifty-six cases of patients with acute cerebral infarction in our hospital from January 2014 to January 2016 were selected and divided into research group and control group according to the random number method, with 128 cases in each group. The control group was treated with edaravone on the basis of conventional treatment, while the research group was treated with safflower yellow pigment on the basis of the control group. NIHSS score and inflammation factor changes before and after treatment, and treatment effect of the two groups were observed. Results There was no statistical significance of NIHSS scores in the two groups before treatment (P>0.05); after treatment, NIHSS scores in the two groups were lower than that before treatment, and the treatment group decreased more than that in the control group, the difference was statistically significant (P<0.05). There were no significant differences in the levels of hs-CRP, IL-2, IL-8 and TNF-α between the two groups before treatment (P>0.05); after treatment, they were decreased in the two groups and the treatment group decreased more significantly than the control group, the difference was statistically significant (P<0.05). The effective rate of the treatment group was 95.31%, which was higher than 83.59% in the control group, the difference was statistically significant (P<0.05). Conclusion Safflower yellow pigment combined with edaravone has significant effect in the treatment of acute cerebral infarction, which can improve the prognosis of patients, and safe and reliable.
KEYWORDS: acute cerebral infarction; safflower yellow pigment; edaravone

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