抗生素与糖皮质激素联合治疗老年慢性阻塞性肺气肿的临床效果

李娟

（陕西省富平县医院，陕西 渭南，711700）

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摘要：

目的 观察抗生素与糖皮质激素联合治疗老年慢性阻塞性肺气肿的治疗效果。方法 将我院收治的92例老年慢性阻塞性肺气肿患者作为研究对象，随机分为对照组和研究组，每组46例。两组患者均进行常规治疗，对照组患者在常规治疗上静脉滴注头孢曲松；研究组患者在对照组基础上加用泼尼松。比较两组患者的临床效果。结果 治疗后，两组患者PaO₂ 水平均高于治疗前， PaCO₂ 水平均低于治疗前（P<0.05）；且研究组的血PaO₂ 水平明显高于对照组，而PaCO₂ 水平明显低于对照组（P<0.05）。研究组总有效率为91.30%，明显高于对照组的63.79%，差异具有统计学意义（P<0.05）。研究组不良反应发生率是6.52%，显著低于对照组的13.04%（P<0.05）。结论 抗生素与糖皮质激素联合使用能有效改善老年慢性阻塞性肺气肿患者血气指标，疗效确切。

关键词：联合治疗；糖皮质激素；抗生素；慢性阻塞性肺气肿

中图分类号：R563.3文献标志码：A文章编号：2096-1413(2017)16-0044-02

Clinical effect of antibiotic combined with glucocorticoid in the treatment of senile chronic obstructive pulmonary emphysema
LI Juan
（Fuping County Hospital, Weinan 711700, China）

ABSTRACT: Objective To observe the clinical effect of antibiotic and glucocorticoid in the treatment of senile chronic obstructive emphysema. Methods Ninety two cases of patients with senile chronic obstructive emphysema were selected as the research objects, all the patients were randomly divided into control group and research group, with 46 cases in each group. Two groups of patients were treated with routine therapy, the control group accepted ceftriaxone intravenous drip on the basis of routine therapy; and the research group was given glucocorticoid based on the control group. The therapeutic effects of the two groups were compared. Results After treatment, the PaO₂ levels of two groups were higher than those before treatment, and PaCO₂ levels were lower than those before treatment (P<0.05); and the PaO₂ level of the research group was higher than that of the control group, the PaCO₂ level of the research group was lower than that of the control group (P<0.05). The total effective rate of the research group was 91.30%, which was higher than 63.79% of the control group (P<0.05). The incidence rate of adverse reactions of the research group was 6.52%, which was lower than 13.04% of the control group (P<0.05). Conclusion Using antibiotic and glucocorticoid in the treatment of senile chronic obstructive emphysema can effectively improve the blood indicators, which has definite therapeutic effect.
KEYWORDS: combination therapy; glucocorticoid; antibiotic; chronic obstructive pulmonary emphysema

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