使用缩宫素联合米索前列醇防治子宫收缩乏力性产后出血的临床效果

丁君丽

（陕西省渭南市澄城县医院，陕西 渭南，715200）

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摘要：

目的 分析缩宫素与米索前列醇联合治疗子宫收缩乏力性产后出血的临床效果。方法 选取我院2014年1月至2016年1月收治的180例子宫收缩乏力性产后出血患者为研究对象，根据不同的药物治疗方法将患者分为对照组和研究组，各90例。对照组患者单纯采用缩宫素治疗，研究组患者采用缩宫素联合米索前列醇治疗，观察两组患者的治疗效果，并对两组患者的治疗的总有效率，产后2、24 h内出血量及不良反应发生情况进行比较。结果 研究组患者治疗总有效率为91.11%，高于对照组的76.67%（P<0.05），对照组产后2、24h的出血量分别为（293.27±64.26）mL、（455.88±59.32）mL，均多于研究组的（177.46±68.24）mL、（314.25±36.47）mL；研究组的不良反应发生率为7.78%，对照组的为11.11%，两组均处于较低状态，差异无统计学意义（P>0.05）。结论 缩宫素联合米索前列醇对子宫收缩乏力性产后出血患者的防治效果较好，可降低产妇产后出血量，且安全性高，值得推广使用。

关键词：缩宫素；米索前列醇；宫缩乏力；产后出血

中图分类号：砸473.71文献标志码：A文章编号：2096-1413(2017)08-0142-02

Clinical effect of oxytocin combined with misoprostol in the prevention and treatment of

postpartum hemorrhage caused by uterine contraction
DING Jun-li
(Chengcheng County Hospital, Weinan 715299, China)

ABSTRACT: Objective To analyze the clinical effect of oxytocin combined with misoprostol on postpartum hemorrhage caused by uterine atony. Methods One hundred and eighty patients with postpartum hemorrhage caused by uterine atony admitted and treated in our hospital from January 2014 to January 2016 were selected, and the patients were divided into the control group and the study group according to different treatment, with 90 cases in each group. The patients in the control group were treated purely with oxytocin, while the study group was treated with oxytocin combined with misoprostol. The treatment effect, the blood loss of 2 and 24 h，the adverse reactions of the two groups were observed. Results The total effective rate in the study group was 91.11%，which was higher than 76.67% of the control group，and the blood loss of 2 and 24 h were (177.46±68.24)mL, (314.25±36.47)mL, which were all higher than (293.27±64.26)mL, (455.88±59.32)mL of the control group (P<0.05); the incidence rate of adverse reactions of the study group was 7.78%, while the control group was 11.11%, and there was no statistical difference between the two groups (P>0.05). Conclusion Oxytocin combined with misoprostol in the treatment of postpartum hemorrhage caused by uterine atony has a good prevention and treatment effect as well as high safety, and can reduce the blood loss after delivery, which is worthy to be popularized and applied.
KEYWORDS: oxytocin; misoprostol; uterine atony; postpartum hemorrhage

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