CA199与CA125水平在子宫内膜异位症中的临床诊断价值

苏焕娥

（府谷县中医医院检验科，陕西 榆林，719400）

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摘要：

目的 研究血清CA199与CA125在子宫内膜异位症诊断中的价值。方法 选择2013年8月至2015年8月我院收治的78例因子宫内膜异位症实行手术治疗的患者作为A组，并选择同期正常健康体检者78例作为B 组，对两组CA199、CA125的阳性率与血清表达水平进行测定。结果 A组CA199阳性表达率为74.4%、CA125阳性表达率为89.7%，二者联合检测阳性表达率为94.9%，分别显著高于对照组的2.6%、1.3%及3.8%（P<0.05）。A 组血清中的CA199 水平为（52.26±13.15）U/mL、CA125 水平为（41.26±13.21）U/mL，分别显著高于B组的（21.10±9.45）U/mL、（8.19±3.25）U/mL（P约0.05）。结论 对于子宫内膜异位症患者，检测患者的血清CA125、CA199可清晰了解其子宫内膜异位症情况，两者联合使用时临床诊断数据更准确，值得在临床上推广及应用。

关键词：子宫内膜异位症；CA199；CA125；诊断价值

中图分类号：R711.71文献标志码：A文章编号：2096-1413(2017)05-0073-02

Diagnostic value of serum CA199 and CA125 levels in patients with endometriosis
SU Huan-e
( Department of Laboratory Medicine, Chinese Medicine Hospital of Fugu County, Yulin 719400, China)

ABSTRACT: Objective To investigate the value of serum CA199 and CA125 in diagnosis of endometriosis. Methods Seventy-eight cases of patients with endometriosis who took surgery for treatment from August 2013 to August 2015 in our hospital were selected as group A, and 78 healthy objects in the same period were selected as group B. The positive rate and the levels of CA199 and CA125 in the two groups were measured and compared. Results The positive expression rate of CA199 was 74.4%, the positive rate of CA125 was 89.7% and the positive rate of combined detection was 94.9% in the group A, which were significantly higher than 2.6%, 1.3% and 3.8% in the control group respectively, the differences were statistically significant (P<0.05). The level of serum CA199 in the group A was (52.26 依13.15) U/mL, the level of CA125 was (41.26±13.21) U/mL, which were significantly higher than (21.10±9.45) U/mL、(8.19±3.25) U/mL in the control group respectively, the differences were statistically significant (P <0.05). Conclusion For patients with endometriosis, the detection of the patients' serum CA125, CA199 can clearly understand the situation of endometriosis, and the combination of both clinical diagnostic data is more accurate, which is worth promoting and applicating in clinic.
KEYWORDS: endometriosis; CA199; CA125; diagnostic value

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