强脉冲光联合吡美莫司乳膏治疗面部激素依赖性皮炎疗效观察

刘颖，仵宁

（咸阳市中心医院，陕西 咸阳，712000）

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摘要：

目的 评价强脉冲光联合吡美莫司乳膏对激素依赖性皮炎患者面部皮肤的治疗效果。方法 选取在我院皮肤科门诊就诊的激素依赖性皮炎患者60例，随机分为治疗组和对照组。治疗组（34例）进行强脉冲光联合吡美莫司乳膏治疗，强脉冲光每4周治疗1次，连续5次，吡美莫司乳膏每晚外用1次。对照组（26 例）单纯应用吡美莫司乳膏治疗，每晚1次，连续治疗5个 月。分别在治疗前、后对两组患者进行疗效评价。结果 治疗后两组主观体征和客观体征评分均较治疗前显著改善，差异均有统计学意义（P<0.05）。治疗组与对照组的主观体征有效率分别为82.35%、76.93%，差异没有统计学意义（P>0.05）。客观体征有效率分别为85.29%、57.69%，差异显著（P<0.05）。结论 强脉冲光联合吡美莫司乳膏治疗激素依赖性皮炎有较好的临床疗效。

关键词：强脉冲光；激素依赖性皮炎；吡美莫司

中图分类号：R758.22文献标志码：A文章编号：2096-1413(2017)05-0006-02

Clinical observation of intense pulsed light and pimecrolimus cream in the

treatment of hormone-dependent facial dermatitis
LIU Ying, WU Ning
(Xianyang Central Hospital, Xianyang 712000, China)

ABSTRACT: Objective To evaluate the therapeutic effect of intense pulsed light and pimecrolimus cream in the treatment of hormone -dependent facial dermatitis. Methods Sixty patients with hormone -dependent facial dermatitis in the department of dermatology in our hospital were chosen and randomly divided into treatment group and control group. The treatment group (34 patients) was treated with intense pulsed light and pimecrolimus cream. The intense pulsed light was given with an interval of 4 weeks for 5 months, and pimecrolimus cream was externally used 1 time per night. The control group (26 patients) was only treated with pimecrolimus cream 1 time per night for 5 months. The curative effects were evaluated in the two groups before and after treatment respectively. Results After therapy, the objective symptom and the subjective symptom scores in the two groups were statistically significant (P<0.05). The efficacy rates of objective symptom in the treatment group and the control group were 82.35% and 76.93% respectively, the differences were not statistically significant (P>0.05). The efficacy rate of subjective symptom in the treatment group and the control group were 85.29% and 57.69% respectively, the differences were statistically significant (P <0.05). Conclusion Intense pulsed light and pimecrolimus cream has significant effect in the treatment of hormone-dependent facial dermatitis.
KEYWORDS: intense pulsed light; hormone-dependent dermatitis; pimecrolimus

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