中国学术期刊网络出版总库入编期刊
CNKI中文期刊全文数据库全文收录期刊
中国核心期刊(遴选)数据库全文收录期刊
万方数据——数字化期刊群收录期刊
中文科技期刊数据库全文收录期刊

主管:陕西省卫生健康委员会
主办:西安心身医学研究所
   西安交通大学第一附属医院
国际标准刊号:ISSN2096—1413
国内统一刊号:CN61—1503/R

拜阿斯匹林与阿托伐他汀联合应用对脑梗再发的预防效果观察

张涛

(陕西省商洛市第二人民医院内三科,陕西商洛,726000)

浏览次数:220次 下载次数:466次

摘要:

目的 观察拜阿斯匹林与阿托伐他汀联合应用对脑梗再发的预防效果。方法 120例首发脑梗患者分别通过服用拜阿斯匹林和(或)阿托伐他汀来预防脑梗再发,根据有无联合用药将其分为联合组与对照组,比较两组患者1年的复发情况。结果 两组患者均随访1年,血液流变学及血脂水平均较治疗前出现了明显改善,其中联合组在LDL、HDL的改善幅度要优于对照组(P<0.05)。联合组脑梗复发率为11.67%,明显低于对照组26.67%(P<0.05)。结论 拜阿斯匹林联合阿托伐他汀对首发脑梗患者起到了明显的预防作用,具有临床应用价值。

关键词:拜阿斯匹林;阿托伐他汀;脑梗再发

中图分类号:R743.33文献标志码:A文章编号:2096-1413(2017)01-0029-02

    The preventive effect observation of bayaspirin and atorvastatin combined application on recurrent cerebral infarction
    ZHANG Tao
    (the 3rd Department of Internal Medicine, the 2nd People s Hospital of Shangluo, Shangluo 726000, China)

    ABSTRACT: Objective To observe the preventive effect of bayaspirin and atorvastatin combined application on recurrent cerebral infarction. Methods One hundred and twenty patients with first cerebral infarction patients by taking bayaspirin and (or) atorvastatin to prevent the recurrence of cerebral infarction were selected and divided into combination group and control group, then the recurrence after one year of two groups were compared. Results Both of the two groups were followed up for one year, the blood rheology and blood lipid levels were significantly improved compared with before treatment, and the improvement of LDL and HDL in combination group were better than those of the control group (P<0.05). The combination group of cerebral infarction recurrence rate was 11.67%, which was significantly lower than 26.67% of the control group (P<0.05). Conclusion Bayaspirin combined with atorvastatin for patients with first cerebral infarction has significant preventive effect, which has clinical application value.
    KEYWORDS: bayaspirin; atorvastatin; recurrent cerebral infarction


    参考文献:

    [1] 陈军华,邓永胜,贺建中,等.拜阿斯匹林联合阿托伐他汀预防脑梗再发的临床应用研究[J].井冈山大学学报:自然科学版,2010,31(3):95-97.

    [2] 李芳.拜阿斯匹林联合阿托伐他汀预防脑梗再发的临床价值[J].大家健康:学术版,2015,9(5):143-144.

    [3] 吕远,郭招娜.阿托伐他汀联合肠溶阿司匹林预防脑梗死复发临床研究[J].黑龙江医学,2013,37(7):565-566.

    [4] 曹瑞.阿托伐他汀与氟伐他汀在缺血性脑血管病二级预防中的比较[J].当代医学,2013,19(20):146-147.

    [5] 中国中西医结合学会神经科专业委员会.脑梗死和脑出血中西医结合诊断标准(试行)[J].中国中西医结合杂志,2006:26.

    [6] 蒋树群.阿司匹林联合阿托伐他汀预防脑梗死复发临床疗效研究[J].现代诊断与治疗,2014,25(3):549.

    [7] 何荣芬,刘秀英,袁刚,等.阿司匹林肠溶片联合阿托伐他汀预防脑梗死再发疗效观察[J].中国药师,2012,15(6):863-864.

    [8] 钟国球.脑梗死采用阿托伐他汀联合肠溶阿司匹林预防复发的临床价值探析[J].中国医药科学,2014,4(4):110-111.

    [9] 马轶睿.糖化血红蛋白水平在糖尿病合并脑梗死、脑梗死再发的临床意义探讨[J].当代医学,2011,17(20):68-69.

    [10] 段和力,高竞生,王燕玲,等.幽门螺杆菌感染与再发脑梗死的关系研究[J].中国综合临床,2015,21(8):703-704.

    [11] 华裕鹏.血塞通联合拜阿斯匹林治疗急性脑梗死随机平行对照研究[J].实用中医内科杂志,2014,28(9):56-58.

上一篇不同剂量阿托伐他汀对急性脑梗死患者颈动脉粥样硬化斑块的治疗效果

下一篇脉络宁与银杏达莫注射液用于急性脑梗死的疗效对比