曲安奈德对复杂性视网膜脱离玻璃体切除术后增生性玻璃体视网膜病变发生的预防作用

赵吉飞，解辽琦 * ，杜建英，刘彦章，郑雪丽

咸阳市第一人民医院眼科一病区，陕西 咸阳，712000

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摘要：

目的 研究曲安奈德对复杂性视网膜脱离玻璃体切除术后增生性玻璃体视网膜病变（PVR）发生的预防效果。方法 选取复杂性视网膜脱离患者 80 例（共 120 只眼，双眼患者 40 例、单眼患者 40 例）作为研究对象，根据治疗方法分为治疗组（玻璃体切除术联合玻璃体腔注入曲安奈德治疗）、对照组（单纯的玻璃体切除术），各 40 例。比较两组患者的治疗效果。结果 随访观察 1 年后，两组视力水平≤0.02 的比例均显著下降（P<0.05）；治疗组治疗有效率高于对照组（P<0.05）。治疗组 PVR 发生率为 7.5%，术后视网膜脱离复发率为 5.0%，低于对照组的 30.0%、20.0%，差异显著（P<0.05）。结论 对复杂性视网膜脱离患者采用玻璃体切除术时联合曲安奈德治疗具有较高的临床价值。

关键词：曲安奈德；玻璃体切除术；增生性玻璃体视网膜病变；预防效果

中图分类号：R779.6文献标志码：A文章编号：2096-1413(2018)08-0100-02

Preventive effect of triamcinolone acetonide on proliferative vitreoretinopathy after vitrectomy of complex retinal detachment

ZHAO Ji-fei, XIE Liao-qi *, DU Jian-ying, LIU Yan-zhang, ZHENG Xue-li

(No.1 Ward of Ophthalmology Department, the First People``s Hospital of Xianyang City, Xianyang 712000, China)

ABSTRACT: Objective To study the preventive effect of triamcinolone acetonide on proliferative vitreoretinopathy (PVR) after complex retinal detachment with retinal detachment. Methods A total of 80 patients with complex retinal detachment (120 eyes in total, 40 cases in both eyes and 40 cases in monocular disease) were enrolled in this study. The patients were divided into treatment group (treated with intravitreal injection of triamcinolone acetonide and vitrectomy) and control group (treated with simple vitrectomy) according to the treatment methods, with 40 cases in each group. The treatment effects were compared in the two groups. Results After followed up for 1 year, the ratio of visual acuity ≤0.02 in both groups decreased significantly (P<0.05); the effective rate in the treatment group was higher than that in the control group (P<0.05). The incidence of PVR in the treatment group was 7.5%, the recurrence rate of retinal detachment was 5.0% , which were significantly lower than 30.0% and 20.0% in the control group (P<0.05). Conclusion Triamcinolone acetonide and vitrectomy in the treatment of patients with complex retinal detachment has high clinical value.
KEYWORDS: triamcinolone acetonide; vitrectomy; proliferative vitreoretinopathy; preventive effect

 

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