慢性肝炎患者并发胆囊结石的危险因素分析

王军

（陕西省蒲城县中医医院外科，陕西 渭南，715500）

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摘要：

目的 探讨慢性肝炎患者合并胆囊结石的危险因素，为其临床防治提供一定依据。方法 收集我院2015 年2 月至2017 年2 月收治的320 例慢性肝炎患者为观察组，根据有无合并胆囊结石分为合并胆囊结石组（64 例）和未合并胆囊结石组（256 例），选取同期住院的无肝脏疾病患者200 例为对照组。分别采用单因素以及多因素分析患者合并胆囊结石的危险因素。结果 观察组胆囊结石发生率为20.0%，明显高于对照组的5.0%（10/200），差异具有统计学意义（P<0.05）；单因素分析显示年 龄、饮酒、合并糖尿病及GGT 水平是慢性肝炎合并胆囊结石的危险因素（P<0.05）；通过多因素Logistic 回归分析发现，影响慢 性肝炎合并胆囊结石的独立危险因素有年龄≥50 岁、饮酒史、GGT 水平（P<0.05）。结论 临床中慢性肝炎患者合并胆囊结石 较为常见，年龄≥50 岁、饮酒、GGT 水平较高是慢性肝炎患者合并胆囊结石的独立危险因素。

关键词：慢性肝炎；胆囊结石；危险因素

中图分类号：R575.1 文献标志码：A文章编号：2096-1413(2018)01-0104-02

Risk factors analysis of chronic hepatitis complicated with cholecystolithiasis


WANG Jun
(Surgery Department, Traditional Chinese Medicine Hospital of Pucheng County, Weinan 715500, China)

ABSTRACT: Objective To investigate the risk factors of chronic hepatitis complicated with cholecystolithiasis, so as to provide the basis for clinical prevention and treatment. Methods From February 2015 to February 2017, 320 patients with chronic hepatitis were selected as the observation group and divided into complicating cholecystolithiasis group (n=64) and not complicating cholecystolithiasis group (n=256) according to whether the patients complicated with cholecystolithiasis. A total of 200 hospitalized patients without liver disease during the same period were selected as the control group. The risk factors of complicating cholecystolithiasis were analysed by univariate and multivariate analysis. Results The incidence of cholecystolithiasis in the observation group was 20.0%, which was higher than 5.0% in the control group, and the difference was statistically significant (P<0.05). According to the univariate analysis, the age, drinking, complicating diabetes and level of GGT were the risk factors of chronic hepatitis complicated with cholecystolithiasis (P<0.05). According to the Logistic regression analysis, the independent risk factors for chronic hepatitis patients complicated with cholecystolithiasis had age≥50 years old, drinking and level of GGT (P<0.05). Conclusion Chronic hepatitis complicated with cholecystolithiasis is common in clinic. The age ≥50 years old, drinking and higher level of GGT are the independent risk factors for chronic hepatitis patients complicated with cholecystolithiasis.
KEYWORDS: chronic hepatitis; cholecystolithiasis; risk factors

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