无创正压通气与丹参川芎嗪注射液联合治疗老年肺心病的临床价值

佘飞龙

（定边县人民医院呼吸内科，陕西 榆林，718699）

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摘要：

目的 探讨无创正压通气与丹参川芎嗪注射液联合治疗老年肺心病的临床价值。方法 以2015年1月至2017年1月收治的80例老年肺心病患者为研究对象，根据采取治疗方法的不同分为对照组与观察组，各40例。对照组采取无创正压通 气治疗，观察组采取无创正压通气联合丹参川芎嗪注射液治疗。比较两组患者治疗效果及治疗前、后心肺功能各项指标 水平。结果 观察组患者治疗总有效率明显高于对照组（P<0.05）；治疗后，两组的LVEF、FEV1/FVC、FEV1%均较治疗前升高，mPAP 较治疗前降低，且观察组LVEF、FEV1/FVC、FEV1%、E/A均高于对照组，mPAP 低于对照组，差异均显著（P<0.05）。 结论 无创正压通气与丹参川芎嗪注射液联合治疗老年肺心病患者具有显著的疗效，能有效改善患者的心肺功能。

关键词：肺源性心脏病；无创正压通气；丹参川芎嗪

中图分类号：R541.5文献标志码：A文章编号：2096-1413(2018)01-0034-02

Clinical value of noninvasive positive pressure ventilation combined with salviae miltiorrhizae and ligustrazine hydrochloride injection in of elderly patients with pulmonary heart disease

SHE Fei-long
(Respiratory Department, the People``s Hospital of Dingbian County, Yulin 718699, China)

ABSTRACT: Objective To investigate the clinical value of noninvasive positive pressure ventilation (NPPV) combined with salviae miltiorrhizae and ligustrazine hydrochloride injection in elderly patients with pulmonary heart disease. Methods A total of 80 elderly patients with pulmonary heart disease admitted from January 2015 to January 2017 were divided into control group and observation group according to the different treatment methods, with 40 cases in each group. The control group was treated with NPPV, and the observation group was treated with NPPV combined with salviae miltiorrhizae and ligustrazine hydrochloride injection. The therapeutic effect and the levels of cardiopulmonary function indexes before and after treatment were compared between the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group (P<0.05). After treatment, the LVEF, FEV1/FVC, FEV1% in both groups increased, mPAP decreased; and the LVEF, FEV1/FVC, FEV1% and E/A in the observation group were higher than those in the control group, mPAP was lower than that in the control group, the differences were significant (P<0.05). Conclusion NPPV combined with salviae miltiorrhizae and ligustrazine hydrochloride injection in the treatment of elderly patients with pulmonary heart disease has significant effect, which can effectively improve the patients`` heart and lung function.
KEYWORDS: pulmonary heart disease; noninvasive positive pressure ventilation (NPPV); salviae miltiorrhizae and ligustrazine

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