结直肠癌术后手术部位切口感染的预后因素分析

高标

（徐州市铜山区人民医院，江苏 徐州，221100）

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摘要：

目的 探讨结直肠癌术后手术部位切口感染的预后因素。方法 在我院2009年1 月至2016 年12 月收治的行结直肠癌 择期手术的患者中随机抽取100 例作研究对象，对其有关术后切口感染的临床资料进行回顾性分析，以单因素、多因素Logistic 回归分析结直肠癌术后手术部位切口感染的预后因素。结果 本组100 例患者术后共发生手术部位切口感染29 例，发 生率为29.00%。性别、年龄与术后手术部位切口感染无关（P>0.05）；体重指数、手术时间、切口长度、术前放化疗、腹腔镜手 术、联合器官切除、术中出血可影响术后手术部位切口感染（P<0.01）。Logistic 回归分析结果显示，手术时间、体重指数、术前 放化疗、联合器官切除是结直肠癌术后手术部位发生切口感染的独立危险因素，而腹腔镜手术是患者术后手术部位发生切 口感染的保护性因素（P<0.05）。结论 手术时间、体重指数、术前放化疗、联合器官切除均为结直肠癌手术患者术后发生切口 感染的独立危险因素，应加强对结直肠癌手术患者围术期的个体化干预，从而降低术后切口感染发生率。

关键词：结直肠癌手术；手术部位切口感染；预后因素；多因素Logistic 回归分析

中图分类号：R735.35 文献标志码：A文章编号：2096-1413(2017)36-0017-02

Prognostic factors of surgical site incision infection after surgery in colorectal cancer
GAO Biao
(People``s Hospital of Tongshan District, Xuzhou 221100, China)

ABSTRACT: Objective To investigate the prognostic factors of surgical site incision infection after surgery in colorectal cancer. Methods From January 2009 to December 2016, 100 cases of patients undergoing elective surgery for colorectal cancer were randomly selected as the study objects. The clinical data of postoperative incisional infection were analyzed retrospectively, and univariate and multivariate logistic regression analysis were used to analyze the prognostic factors of incision infection in postoperative colorectal cancer surgery. Results Of the 100 patients, surgical site incision infection after surgery occurred in 29 cases, and the incidence rate was 29.00%. The sex, age were not related to the surgical site incision infection (P >0.05); the body mass index, operative time, incision length, preoperative chemoradiotherapy, laparoscopic surgery, combined organ resection and intraoperative hemorrhage could affect the surgical site incision infection (P<0.01). Logistic analysis showed that body mass index, operative time, incision length, preoperative chemoradiotherapy and combined organ resection were the independent risk factors, and laparoscopic surgery was protective factors of surgical site incision infection after surgery (P <0.05). Conclusion The operation time, body mass index, preoperative chemoradiotherapy and combined organ resection were independent risk factors for incision infection in patients with colorectal cancer surgery, individualized intervention should be strengthened during the perioperative period to reduce the incidence of postoperative incision infection.
KEYWORDS: colorectal cancer surgery; surgical site incision infection; prognostic factors; multivariate Logistic regression analysis

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