兰索拉唑和奥美拉唑配合抗生素治疗酒精型消化溃疡的疗效对比分析

吴秋菊

（渭南市第二医院消化内科，陕西 渭南，714000）

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摘要：

目的 研究兰索拉唑和奥美拉唑配合抗生素治疗酒精型消化溃疡的临床疗效。方法 选择2016年1月至2017年3月来我院治疗的80例酒精型消化溃疡患者，按照入院治疗的先后顺序分为A组与B组，其中为A组的40例患者运用兰索拉唑配合 抗生素治疗，为B 组的40 例患者运用奥美拉唑配合抗生素治疗，比较两组患者的临床效果。结果 治疗后，两组患者的临床症状 均得到相应的改善，其中A 组患者的腹痛和反酸症状发生率显著低于B 组（P<0.05）；A 组不良反应总发生率为10.00%，明显低 于B组的40.00%（P<0.05）。A 组患者的治疗总有效率为97.50%，而B 组为82.50%，组间差异显著（P<0.05）。结论 兰索拉唑与奥 美拉唑在治疗酒精型消化溃疡方面均具有一定的疗效，其中兰索拉唑治疗总有效率更高，不良反应更少。

关键词：兰索拉唑；奥美拉唑；酒精型消化溃疡

中图分类号：R573.1文献标志码：A文章编号：2096-1413(2017)35-0038-02

Effect comparative analysis of lansoprazole and omeprazole combined with antibiotics in the treatment

of alcoholic type peptic ulcer
WU Qiu-ju
(Gastroenterology Department, the Second Hospital of Weinan, Weinan 714000, China)

ABSTRACT: Objective To study the efficacy of lansoprazole and omeprazole combined with antibiotics in the treatment of alcoholic type peptic ulcer. Methods Eighty cases of patients with alcoholic type peptic ulcer admitted in our hospital from January 2016 to March 2017 were selected, and divided into group A and group B according to the admission order, with 40 cases in each group. The group A was treated with lansoprazole combined with antibiotics, and the group B was treated with omeprazole combined with antibiotics, then the clinical efficacy of the two groups were compared. Results After treatment, the clinical symptoms of both groups improved correspondingly. The incidence rates of abdominal pain and acid reflux symptoms in group A were significantly lower than those in the group B (P<0.05). The total incidence rate of adverse reactions in the group A was 10.00%, which was significantly lower than 40.00% in the group B (P<0.05). The total effective rate of treatment in the group A was 97.50%, while it was 82.50% in the group B, the difference was statistically significant (P<0.05). Conclusion Lansoprazole and omeprazole both has certain curative effect in the treatment of alcoholic type peptic ulcer, but the former has higher total effective rate and fewer adverse reactions.
KEYWORDS: lansoprazole; omeprazole; alcoholic type peptic ulcer

参考文献：
[1] 郑慧英.兰索拉唑和奥美拉唑配合抗生素等治疗酒精型消化溃疡 疗效对比分析[J].大家健康:学术版,2015,6(2):147.
[2] 王玲.用兰索拉唑和奥美拉唑治疗酒精型消化溃疡的效果对比[J]. 当代医药论丛,2015,13(18):155-156.
[3] 乌兰图雅.兰索拉唑和奥美拉唑配合抗生素治疗酒精型消化溃疡 的价值[J].中外医学研究,2015,13(35):46-48.
[4] 梁凤铭,彭锡其.兰索拉唑和奥美拉唑并用抗生素治疗酒精型消化 溃疡对比分析[J].深圳中西医结合杂志,2016,26(6):118-119.
[5] 郭羽.兰索拉唑和奥美拉唑配合抗生素等治疗酒精型消化溃疡疗 效对比分析[J].河北医学,2014,20(3):463-466.
[6] 任少敏.奥美拉唑与兰索拉唑配合抗生素对酒精型消化溃疡的疗 效[J].中国卫生产业,2013,11(5):60,62.
[7] 邓志鹏.兰索拉唑和奥美拉唑联合抗生素治疗酒精型消化性溃疡 的疗效[J].医疗装备,2016,29(23):64-65.
[8] 吴江涛.兰索拉唑与奥美拉唑治疗酒精型消化性溃疡的临床疗效 比较[J].实用药物与临床,2012,15(12):846-847.
[9] 张嘉刚. 兰索拉唑与奥美拉唑治疗酒精型消化性溃疡的疗效比 较[J].中国老年学杂志,2011,31(17):3253-3254.