小剂量多虑平联合心理治疗对脑梗死后抑郁的疗效观察

张培荣，王万虎，陈素芳

（陇县人民医院，陕西 宝鸡，721200）

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摘要：

目的 探讨小剂量多虑平联合心理治疗对脑梗死后抑郁的疗效。方法 选取本院接受治疗的68例脑梗死后抑郁患者为 研究对象，随机分为对照组和观察组，每组34例。对照组给予患者小剂量多虑平治疗，在此基础上观察组采取心理治疗。比较 两组患者的疗效，MMSE、HAMD评分及Barthel指数和患者的脑神经功能及心理状态恢复正常时间。结果 观察组的治疗总有效率为97.06%，明显高于对照组的76.47%（P<0.05）。治疗4周后，两组患者的MMSE、HAMD 评分、Barthel 指数均显著改善，且观察组均明显优于对照组（P<0.05）。观察组患者脑神经功能恢复正常时间、心理状态恢复正常时间均明显短于对照组（P< 0.05）。结论 小剂量多虑平联合心理疗法治疗脑梗死后抑郁效果显著，有利于其脑神经功能和心理状态尽快恢复正常。

关键词：小剂量多虑平；心理治疗；脑梗死后抑郁

中图分类号：R749.1文献标志码：A文章编号：2096-1413(2017)35-0034-02

Effect observation of low-dose doxepin combined with psychological therapy on depression after cerebral infarction
ZHANG Pei-rong, WANG Wan-hu, CHEN Su-fang


(People``s Hospital of Long County, Baoji 721200, China)

ABSTRACT: Objective To study the curative effect of low-dose doxepin combined with psychological therapy on depression after cerebral infarction. Methods A total of 68 cases of patients with depression after cerebral infarction admitted in our hospital were selected and randomly divided into control group and observation group, with 34 cases in each group. The patients in the control group were treated with low-dose doxepin, and on the basis, the patients in the observation group were treated with psychological therapy. The efficacy, the scores of MMSE, HAMD scores and Barthel index, the recovery time of brain function and psychological state were compared between the two groups. Results The total effective rate of treatment in the observation group was 97.06%, which was significantly higher than 76.47% in the control group (P<0.05). After treatment for 4 weeks, the scores of MMSE, HAMD scores and Barthel index in the two groups significantly improved, and those in the observation group were obviously better than the control group (P<0.05). The recovery time of brain function and psychological state were significantly shorter than those in the control group (P<0.05). Conclusion The combination of low-dose doxepin and psychological therapy on depression after cerebral infarction has significant effect and can be conducive to enhance the recovery of brain function and psychological state.
KEYWORDS: low-dose doxepin; psychological therapy; depression after cerebral infarction

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