氨氯地平联合依那普利/叶酸片治疗H 型高血压的临床疗效

李家军

（陕西省安康市旬阳县中医院，陕西 安康，725700）

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摘要：

目的 研究氨氯地平联合依那普利/叶酸片对H 型高血压的临床疗效。方法 选取我院2014 年6 月至2016 年6 月收治 的50 例H 型高血压患者，按照随机数字表法分为观察组和对照组，每组25 例，患者均在试验前一周停止使用其他降压 药，观察组患者使用氨氯地平联合依那普利/叶酸片治疗，对照组患者使用氨氯地平片治疗，比较两组患者治疗效果和不 良反应发生情况。结果 观察组治疗总有效率为92.00%（23/25），明显高于对照组的76.00%（19/25）（P<0.05）；观察组的 不良反应总发生率为8.00%（2/25），明显低于对照组的24.00%（6/25），差异具有统计学意义（P<0.05）。结论与单一使用 氨氯地平片治疗比较，采用氨氯地平联合依那普利/叶酸片对H 型高血压患者进行治疗，效果更好，不良反应发生率更 低，值得临床推广。

关键词：氨氯地平；依那普利；叶酸；H 型高血压

中图分类号：R972.4 文献标志码：A文章编号：2096-1413(2017)33-0034-02

Clinical efficacy of amlodipine combined with enalapril / folic acid in the treatment of H type hypertension
LI Jia-Jun
(Xunyang County Traditional Chinese Medicine Hospital, Ankang 725700, China)

ABSTRACT: Objective To discuss the clinical efficacy of amlodipine combined with enalapril / folic acid in the treatment of H type hypertension. Methods A total of 50 patients with H type hypertension admitted in our hospital from June 2014 to June 2016 were selected and divided into observation group and control group according to the random table method, with 25 cases in each group. All patients were stopped giving antihypertensive drugs, the patients in the observation group were given amlodipine combined with enalapril/folic acid, while the patients in the control group were given amlodipine alone. The treatment efficacy and incidence of adverse reactions were compared between the two groups. Results The total effective rate of the observation group was 92.00% (23/25), which was significantly higher than 76.00% (19/25) of the control group (P<0.05). The total incidence of adverse reactions in the observation group was 8.00% (2/25), which was obviously lower than 24.00% (6/25) in the control group (P<0.05). Conclusion Compared with using amlodipine alone, amlodipine combined with enalapril / folic acid for the treatment of H type hypertension has better clinical efficacy and lower incidence of adverse reactions, which is worthy of clinical promotion.
KEYWORDS: amlodipine; enalapril; folic acid; H type hypertension

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