美托洛尔单用与联合贝那普利治疗慢性肺源性心脏病的临床效果比较

姚丹梅1，李小波2

（1.陕西省咸阳彩虹医院，陕西 咸阳，712021；2. 榆林市神木市医院，陕西 榆林，719300）

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摘要：

目的 比较美托洛尔单用与联合贝那普利治疗慢性肺源性心脏病的临床效果。方法 选取2014年10月至2016年10月我 院收治的180例慢性肺源性心脏病患者，所有患者均随机分对照组与观察组，其中对照组予以单一美托洛尔进行治疗，观察组在对照组基础上予以贝那普利进行治疗，比较分析两组血气功能（血氧饱和度、血二氧化碳分压、心脏每搏输出量、左心室射血 分数）及临床效果。结果 观察组血气功能治疗情况[血氧饱和度（93.56依10.70）%、血二氧化碳分压（43.20±5.42）mmHg、心脏每 搏输出量（70.10±5.05）mL、左心室射血分数（66.35±5.25）%]及临床总有效率（94.44%）均优于对照组[血氧饱和度（84.60±10.45）%、血二氧化碳分压（57.65±5.58）mmHg、心脏每搏输出量（56.50±6.30）mL、左心室射血分数（54.40±5.10）%、临床总有效 率（75.56%）（]P<0.05）。结论 对慢性肺源性心脏病患者联合使用贝那普利与美托洛尔进行治疗临床治疗效果优于单一使用 美托洛尔，值得推广。

关键词：慢性肺源性心脏病；贝那普利；美托洛尔

中图分类号：R541.5文献标志码：A文章编号：2096-1413(2017)29-0015-02

Clinical efficacy comparison of metoprolol and metoprolol combined with benazepril in treatment of

chronic pulmonary heart disease
YAO Dan-mei 1, LI Xiao-bo 2
(1. Xianyang Caihong Hospital, Xianyang 712021; 2. Shenmu Hospital, Yulin 719300, China)

ABSTRACT: Objective To compare the clinical efficacy of metoprolol and metoproloc combined with benazepril in the treatment of chronic pulmonary heart disease. Methods One hundred and eighty patients with chronic pulmonary heart disease treated between October 2014 and October 2016 in our hospital were selected and randomly divided into control group and observation group. The patients in the control group were treated with metoprolol alone, while the patients in the observation group were treated with metoprolol combined with benazepril. The blood gas conditions (oxygen saturation, partial pressure of carbon dioxide, stroke volume and left ventricular ejection fraction) and clinical effects of the two groups were compared and analyzed. Results The oxygen saturation, partial pressure of carbon dioxide, stroke volume and left ventricular ejection fraction of the observation group were（93.56±10.70）%,（43.20±5.42）mmHg,（70.10±5.05）mL and（66.35±5.25）%, which were significantly better than those of the control group [(84.60±10.45)%, （57.65±5.58）mmHg, (56.50±6.30) mL and (54.40±5.10)%]. In addition, the total effective rate of the control group (75.56%) was significantly lower than that of the observation group (94.44%) (P<0.05). Conclusion The clinical effect of metoprolol combined with benazepril in the treatment of chronic pulmonary heart disease is better than using metoprolol alone, which is worthy of popularization in clinic.

KEYWORDS: chronic pulmonary heart disease; benazepril; metoprolol

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