归肾丸合生化汤联合雌孕激素预防宫腔手术后宫腔粘连临床效果
刘亚妮，符雅惠，严妮子，孟凡峰
（陕西中医药大学第二附属医院，陕西 咸阳，712000）
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摘要：
目的 探讨归肾丸合生化汤联合雌孕激素预防宫腔手术后宫腔粘连的临床效果。方法 选择于我院进行宫腔手术的120例患者为研究对象，随机分为试验组和对照组，各60例。所有患者术后均进行常规抗生素治疗，对照组患者给予雌孕激素治疗，试验组在对照组基础上给予归肾丸合生化汤。比较两组患者术后首次月经复潮时间、子宫内膜厚度，以及腹痛、月经量减少及宫腔粘连发生情况。结果 治疗后，试验组患者首次月经复潮时间为（28.30±2.97）d，与对照组的（27.30±3.54）d 比较，差异 无统计学意义（P>0.05）。治疗后，试验组患者子宫内膜厚度为（7.47±1.57）mm，明显优于对照组的（5.02±1.25）mm，差异具有统计学意义（P<0.05）。试验组患者术后并发症总发生率为5.00%，明显低于对照组患者的21.67%，差异具有统计学意义（P< 0.05）。结论 归肾丸合生化汤联合雌孕激素对宫腔手术后宫腔粘连的预防效果显著，安全性强，值得在临床推广应用。
关键词：宫腔粘连；归肾丸合生化汤；雌孕激素
中图分类号：R713文献标志码：A文章编号：2096-1413(2017)27-0118-02
Clinical effect of Guishen pills and Shenghua decoction combined with estrogen and progesterone hormones
in the prevention of intrauterine adhesions after intrauterine surgery
LIU Ya-ni, FU Ya-hui, YAN Ni-zi, MENG Fan-feng
(the Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, China)
ABSTRACT: Objective To explore the clinical effect of Guishen pills and Shenghua decoction combined with estrogen and progesterone hormones in the prevention of intrauterine adhesions after intrauterine surgery. Methods A total of 120 cases of patients who accepted intrauterine surgery in our hospital were selected and randomly divided into experimental group and control group, with 60 cases in each group. All the patients were treated with conventional antibiotics treatment, the control group accepted estrogen and progesterone hormones, and the experimental group received Guishen pills and Shenghua decoction on the basis of the control group. The first menstrual cycle time, endometrial thickness, and incidences of abdominal pain, menstrual loss and intrauterine adhesions were compared between the two groups. Results After treatment, the first menstrual cycle time of the experimental was (28.30±2.97) d, there was no significant difference compared with (27.30±3.54) d of the control group (P>0.05). After treatment, the endometrial thickness of the experimental was (7.47±1.57) mm, there was significant difference compared with (5.02±1.25) mm of the control group (P<0.05). The incidence rate of postoperative complications of the experimental group was 5.00%, which was lower than 21.67% of the control group (P<0.05). Conclusion The clinical effect of Guishen pills and Shenghua decoction combined with estrogen and progesterone hormones in the prevention of intrauterine adhesions after intrauterine surgery is significant. It has high safety, which is worthy of clinical application and popularization.
KEYWORDS: intrauterine adhesions; Guishen pills and Shenghua decoction; estrogen and progesterone hormones
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