胰腺癌患者CD59表达与术后腹腔感染的相关性分析

牟洪香，王爱萍

（山东省青州荣军医院，山东 潍坊，262500）

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摘要：

目的 分析早期胰腺癌患者CD59 表达与胰腺癌术后并发腹腔感染的相关性，为胰腺癌术后腹腔感染的诊治及护理提供参考依据。方法 选取2013年7月至2016年9月我院收治的40 例确诊为胰腺癌术后并发腹腔感染的患者为A组，另选取同期35例胰腺癌术后无腹腔感染的患者为B 组，比较两组患者的CD59表达，分析其与胰腺癌术后并发腹腔感染的关 系。结果 A 组患者CD59 阳性率为65.00%，明显高于B组的34.29%，差异具有统计学意义（P<0.05），且腹腔感染程度与CD59表达呈正相关，差异有统计学意义（r=0.564，P<0.05），腹腔感染程度越高，CD59的表达越高（P<0.05）。结论 通过血清检测CD59的表达，可以判断胰腺癌手术后是否并发腹腔感染，且CD59阳性表达率越高，腹腔感染程度会相应增高，这对胰腺癌患者是否有必要开展手术提供了必要的临床参考价值，临床应予以重视。

关键词：CD59；胰腺癌；腹腔感染

中图分类号：R656文献标志码：A文章编号：2096-1413(2017)27-0014-02

Correlative analysis of CD59 expression and intraperitoneal infection in patients with pancreatic cancer
MU Hong-xiang, WANG Ai-ping
(Shandong Qingzhou Disabled Soldier Hospital, Weifang 262500, China)

ABSTRACT: Objective To analyze the correlation between CD59 expression and peritoneal infection in patients with early pancreatic cancer, so as to provide reference for diagnosis and treatment of postoperative abdominal infection of pancreatic cancer. Methods Forty cases of confirmed pancreatic cancer patients with postoperative abdominal infection in our hospital from July 2013 to September 2016 were selected as the group A, and another 35 cases of patients with pancreatic cancer without postoperative abdominal infection were set as the group B. The expression of CD59 was compared between the two groups, and the relationship between the expression of CD59 and peritoneal infection in patients with early pancreatic cancer were analyzed. Results The positive rate of CD59 in group A was 65.00% , which was significantly higher than 34.29% in group B, the difference was statistically significant (P<0.05), and there was a positive correlation between the degree of abdominal infection and CD59 expression, the difference was statistically significant (r=0.564, P<0.05), the higher the degree of abdominal infection, the higher the expression of CD59 (P<0.05). Conclusion By detecting the expression of CD59 in serum, it can judge whether abdominal infection occurs after surgery in patients with pancreatic cancer, and CD59 positive expression rate is higher, the degree of abdominal infection will increase accordingly. It provides the necessary clinical surgery reference for patients with pancreatic cancer, which is worthy of clinical attention.
KEYWORDS: CD59; pancreatic cancer; abdominal cavity infection

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