放射介入治疗应用在肝癌治疗中的临床疗效

王明利，贾一松，冯琦，董莉

（陕西省宝鸡市中医医院，陕西 宝鸡，721001）

浏览次数：89次 下载次数：372次

摘要：

目的 对放射介入治疗应用在肝癌中的临床疗效进行观察分析。方法 选取我院2013年6月至2014年6月收治的原发性肝癌患者112例作为本次研究的对象，所有患者均给予肝动脉化疗栓塞介入治疗，观察患者的临床治疗效果。结果 巨块型肝癌患者治疗有效率为76.4%，弥漫型患者有效率为89.7%，结节型患者有效率为72.2%，治疗总有效率为80.4%。弥漫型患者有效率高于其他类型患者（P<0.05）。患者18个月后的生存率为75.0%。19 例出现不良反应。结论 肝动脉化疗栓塞介入治疗原发性肝癌患者的效果较好，操作简便，可有效延长患者的生存期，值得在临床推广应用。

关键词：肝动脉化疗栓塞介入治疗；原发性肝癌；生存期

中图分类号：R735.7文献标志码：A文章编号：2096-1413(2017)21-0019-02

Clinical efficacy of interventional radiology treatment on primary hepatic carcinoma
WANG Ming-li, JIA Yi-song, FENG Qi, DONG Li
（Chinese Medicine Hospital of Baoji, Baoji 721001, China）

ABSTRACT: Objective To investigate the clinical efficacy of interventional radiology treatment on primary hepatic carcinoma. Methods One hundred and twelve cases of patients with primary hepatic carcinoma admitted in our hospital from June 2013 to June 2014 were selected as the experimental subjects in this study. All the patients were treated with hepatic artery chemotherapy and interventional embolization treatment, the therapeutic effect was observed. Results The therapeutic effective rate in patients with massive hepatocellular carcinoma was 76.4%, the therapeutic effective rate in patients with diffuse hepatocellular carcinoma was 89.7%, the therapeutic effective rate in patients with nodular melanoma hepatocellular carcinoma was 72.2%, the overall treatment efficiency was 80.4%. The effective rate of patients with diffuse hepatocellular carcinom were higher than that of other types of patients (P<0.05). After 18 months follow-up, the survival rate was 75.0%,and adverse reactions occurred in 19 cases of patients. Conclusion The hepatic artery chemotherapy and interventional embolization treatment has a great effect in patients with primary hepatic carcinoma, and is easy to operate. It can effectively prolong the survival of patients and is worth to be popularized and applied in clinic.
KEYWORDS: hepatic artery chemotherapy and interventional embolization treatment; primary hepatic carcinoma; survival rate

参考文献：
[1] 林睿英.原发性肝细胞癌射频消融治疗前后的核磁共振成像影像分析[D].福州:福建医科大学,2014.
[2] HO MC,HASEGAWA K,CHEN XP,et al.Surgery for intermediate and advanced hepatocellular carcinoma: a consensus report from the 5th asia-pacific primary liver cancer expert meeting (APPLE 2014) [J].Liver Cancer,2016,5(4):245-256.
[3] 孟照华,孟宪欣,米文宁,等.肝动脉化疗栓塞联合经皮肝瘤内注射治疗中晚期肝癌的临床分析[J].中国肿瘤临床,2010,37(12):710-712.
[4] 蒋明,马华兵,杨瑞梅,等.肝动脉化疗栓塞治疗原发性肝癌200例分析[J].当代医学,2012,18(27):70-71.
[5] 沈海洋,杨光,刘瑞宝,等.原发性肝癌患者肝动脉化疗栓塞术后肝区疼痛的临床意义[J].介入放射学杂志,2010,19(4):297-300.
[6] 谭莉萍,岑洪,胡晓桦.实体瘤疗效评价标准的历史、现状及其存在的问题[J].医学综述,2009,15(10):1492-1494.
[7] 徐兴明,滕红,谢英,等.放射介入联合微波消融在转移性肝癌治疗中的应用[J].中国医药导刊,2015,17(9):868-869,872.
[8] 张志伟.原发性肝癌放射介入治疗分析[J].当代医学,2011,17(27):70-71.
[9] 曹瑞锋,陈涛,唐育斌,等.TSGF、CEA、AFP 联合检测在肝癌放射介入治疗中的价值[J].中国保健营养(下旬刊),2014,24(3):1411-1412.
[10] 娄明武,王徽,高天俊,等.巴曲酶灌注联合肝动脉化疗栓塞治疗原发性肝癌的临床初步研究[J].中华肿瘤杂志,2010,32(5):373-376.
[11] 杜玉姣.放射介入治疗高龄肝癌患者的健康教育情况分析[J].数理医药学杂志,2011,24(6):700-701.