硫酸镁联合硝苯地平治疗妊娠期高血压的临床效果分析

王春梅

（陕西省府谷县中医医院妇产科，陕西 榆林，719400）

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摘要：

目的 探讨硫酸镁联合硝苯地平治疗妊娠期高血压的临床效果。方法 选取我院2013年5月至2016年5月收治的130例妊娠期高血压患者为研究对象，按照随机数字表法将其分为两组，各65例。对照组给予硫酸镁治疗，研究组采用硫酸镁联合硝苯地平治疗，观察两组患者的临床治疗效果、治疗前后血压的变化及不良反应发生情况。结果 研究组患者的治疗总有效率及不良反应均显著优于对照组，两组比较差异显著（P<0.05），两组治疗后血压较治疗前均有所下降，但研究组下降幅度显著优于对照组，差异具有统计学意义（P<0.05）。结论 对妊娠期高血压患者采用硫酸镁联合硝苯地平治疗，能显著降低血压，且不良反应少，具有重要的应用价值。

关键词：妊娠期高血压；硫酸镁；硝苯地平；不良反应

中图分类号：R714.246文献标志码：A文章编号：2096-1413(2016)27-0075-02

Analysis of the clinical effect of magnesium sulfate combined with nifedipine in the treatment of hypertensive disorder complicating pregnancy
WANG Chun-mei
(Department of Gynaecology and Obstetrics, TMC Hospital of Fugu County, Yulin 719400, China)

ABSTRACT: Objective To investigate the clinical effect of magnesium sulfate combined with nifedipine in the treatment of hypertensive disorder complicating pregnancy. Methods One hundred and thirty cases of patients with hypertensive disorder complicating pregnancy in our hospital from May 2013 to May 2016 were selected and divided into two groups, with 65 cases in each group. The control group was treated with magnesium sulfate therapy, and the study group received magnesium sulfate combined with nifedipine. The clinical effect, the changes in blood pressure before and after treatment and adverse reactions were compared between the two groups. Results The clinical effect and adverse reactions of the study group were significantly better than those of the control group (P<0.05). Compared with those before treatment, the blood pressure of patients after treatment decreased, and the falling ranges of the study group were significantly higher than those of the control group, the differences were significant (P<0.05). Conclusion Magnesium sulfate combined with nifedipine can significantly reduce blood pressure of patients with gestational hypertension, and reduce the adverse reaction, which has important application value.
KEYWORDS: hypertensive disorder complicating pregnancy; magnesium sulfate; nifedipine; adverse reactions

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