阿奇霉素在儿科临床应用中的不良反应研究
苏红英
（千阳县人民医院，陕西 宝鸡，721100）
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摘要：
目的 探讨阿奇霉素在儿科临床应用中的不良反应。方法 选取我院2013年3月至2015年6月收治的120例儿科患儿，按照患儿住院的先后顺序，分成观察组和对照组，各60例。两组患儿均通过阿奇霉素治疗，观察组经口服的方式治疗，对照组采取静脉注射的方式治疗，比较两组患儿的临床效果及不良反应发生情况。结果 观察组治疗总有效率为95.00%,对照组治疗总有效率为93.33%,差异无统计学意义（P>0.05）；观察组患儿的不良反应发生率5.00%，明显低于对照组的不良反应发生率28.33%，差异具有统计学意义（P<0.05）。结论 儿科中应用阿奇霉素治疗，易发生胃肠道不良反应，但经口服，治疗更加安全，值得临床深入推广。
关键词：阿奇霉素；儿科；胃肠道反应
中图分类号：R95文献标志码：A文章编号：2096-1413(2017)08-0105-02
Adverse reactions study of azithromycin in pediatric clinical application
SU Hong-ying
(People`s Hospital of Qianyang County, Baoji 721100, China)
ABSTRACT: Objective To explore the adverse reactions of azithromycin in pediatric clinical application. Methods One hundred and twenty cases of pediatric patients in our hospital from March 2013 to June 2015 were selected, and all the patients were divided into observation group and control group according to the order of admission, with 60 cases in each group. Two groups of children all received azithromycin, the observation group was treated with oral treatment, while the control group received intravenous treatment. The clinical effects and adverse reactions of two groups were compared. Results The total effective rate of the observation group was 95.00%, which of the control group was 93.33%, there was no significant difference between the two groups (P<0.05). The adverse reaction rate of the observation group was 5.00%, which was lower than 28.33% of the control group (P<0.05). Conclusion Using azithromycin in the treatment for pediatric is easy to occur gastrointestinal adverse reactions，but the oral treatment is more safe，and it is worthy of clinical application.
KEYWORDS: azithromycin; pediatrics; gastrointestinal adverse reactions
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