慢性心力衰竭患者经硝酸甘油治疗的效果探析

邓益平

（陕西省商洛市镇安县中医医院内科，陕西 商洛，711500）

浏览次数：90次 下载次数：357次

摘要：

目的 探讨给予慢性心力衰竭患者硝酸甘油治疗的临床效果。方法 抽选2014年1月至2016年2月在我院内科接受救治的慢性心力衰竭患者200例为研究对象，根据患者入院时间先后分为对照组和观察组。对照组（100例）患者给予卧床休息、 病因控制等常规治疗措施，观察组（100例）患者则在此基础上添加硝酸甘油静脉滴注治疗，对比两组患者治疗总有效率及不良反应发生率。结果 观察组患者治疗总有效率（95.0%）高于对照组患者（74.0%），差异有统计学意义（P<0.05）。观察组患者不良反应发生率（2.0%）与对照组患者（3.0%）相比，无显著差异（P>0.05）。结论 在常规治疗基础上添加硝酸甘油治疗慢性心力衰竭患者，效果确切，同时安全性高，值得临床推广。

关键词：慢性心力衰竭；硝酸甘油；治疗有效率；不良反应

中图分类号：R541.6文献标志码：A文章编号：2096-1413(2017)08-0042-02

Analysis of therapeutic effect of nitroglycerin on patients with chronic heart failure
DENG Yi-ping
(Medical Department, Zhen`an County Chinese Traditional Medicine Hospital, Shangluo 711500, China)

ABSTRACT: Objective To investigate the clinical effect of nitroglycerin in the treatment of patients with chronic heart failure. Methods Two hundred cases of patients with chronic heart failure admitted in medical department of our hospital from January 2014 to feburary 2016 were selected as research objects, which were divided into control group and observation group according to the admission time. The control group (100 cases) was treated with bed rest, symptom control and other conventional treatment, while the observation group (100 cases) accepted intravenous infusion of nitroglycerin treatment on the basis of the control group. The total effective rate and adverse reaction incidence rate were compared between the two groups. Results The total effective rate of the observation group (95.0%) was higher than that of the control group (74.0%), with significant difference (P<0.05). And the incidence rate of adverse reactions (2.0%) in observation group and control group (3.0%) showed no significant difference (P>0.05). Conclusion Nitroglycerin on the basis of routine treatment can significantly improve the treatment effect on chronic heart failure patients, with high safety, and it is worthy of clinical promotion.
KEYWORDS: chronic heart failure; nitroglycerin; treatment efficiency; adverse reaction

参考文献：
[1] 孙婧.静脉滴注硝酸甘油治疗慢性心力衰竭临床疗效观察[J].中国实用医药,2015,10(4):112-113.
[2] 魏艳胜.参麦注射液联合硝酸甘油治疗老年慢性心力衰竭42例 疗效分析[J].中国社区医师,2012,14(18):226.
[3] 欧阳雪莲,陈晓云,杨艳霞,等.高龄慢性心力衰竭患者循证治疗效果分析[J].心血管病防治知识,2014(7):86-88.
[4] 张盛开.不同剂量硝酸甘油治疗慢性心力衰竭的疗效观察及不良反应分析[J].内科,2015,10(2):169-170.
[5] 游海燕,晏萍华.多巴酚丁胺联合硝酸甘油治疗慢性顽固性心力衰竭的效果分析[J].中国当代医药,2015,22(27):102-104.
[6] 吴生明.硝酸甘油联合卡托普利治疗慢性肺源性心脏病心力衰竭的效果观察[J].中国当代医药,2014,21(28):83-85.
[7] 张宏伟.小剂量硝酸甘油配合多巴胺治疗急慢性心力衰竭82例 [J].现代诊断与治疗,2014,25(3):565-566.
[8] 刘云玲.硝酸甘油联合小剂量多巴胺治疗慢性肺源性心脏病心力衰竭疗效探讨[J].心血管病防治知识,2016(2):73-74.
[9] 孟凡强.他汀类药物在慢性心力衰竭治疗中的效果观察[J].当代医学,2013,19(13):6-8.
[10] 刘远水.多巴酚丁胺联合硝酸甘油治疗慢性顽固性心力衰竭的临床分析[J].当代医学,2016,22(9):140-141.