金双岐联合思密达治疗小儿腹泻的临床疗效及安全性分析

卢娟毅

（长安区妇幼保健院，陕西 西安，710100）

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摘要：

目的 针对金双岐联合思密达治疗小儿腹泻的临床疗效及安全性进行分析。方法 选取我院2013年5月至2016年5月收治的100例小儿腹泻患儿作为研究对象，按随机法将其分成观察组与对照组，每组50例患儿。对照组患儿在一般治疗基础上给予思密达口服，观察组患儿在一般治疗基础上采用金双岐联合思密达进行治疗，比较两组小儿腹泻患儿用药治疗 一个疗程（5d）后的临床疗效、症状、体征及不良反应发生情况。结果 观察组小儿腹泻患儿的临床总有效率为98.00%，而对照组患儿的临床总有效率仅有80.00%，观察组患儿的总有效率明显高于对照组（P<0.05）。观察组患儿的退热时间（1.31±0.55）d 明显短于对照组患儿的（2.54±1.45）d（P<0.05）；两组小儿腹泻患儿都未发生明显的不良反应。结论 使用金双岐联合思密达治疗小儿腹泻的临床疗效明显，没有明显的不良反应发生，可在各级医疗单位推广使用。

关键词：金双岐；思密达；小儿腹泻；临床疗效

中图分类号：R725.7 文献标志码：A文章编号：2096-1413(2017)14-0091-02

Clinical effect and safety of golden bifid and smecta in the treatment of infantile diarrhea
LU Juan-yi
（Chang`an District Maternal and Child Health Hospital, Xi`an 710100, China）

ABSTRACT: Objective To explore the clinical effect and safety golden bifid and smecta in the treatment of infantile diarrhea. Methods One hundred children with infantile diarrhea from May 2013 to May 2016 were selected as the research objects，all the patients were randomly divided into observation group and control group, with 50 cases in each group. The patients in the control group received smecta based on the basis of conventional therapy and the observation group was given golden bifid based on the conventional therapy. After 1 course of treatment (5 d), the curative effect, clinical symptoms, physical sign and complication incidence rate of the two groups were compared. Results The total clinical effect of the observation group was 98.00%, which was better than 80.00% of the control group (P<0.05); the antifebrile time of the observation group was (1.31±0.55) d, which was shorter than (2.54±1.45) d of the control group, and the difference was significant (P<0.05). There was no obvious adverse reaction between the two groups. Conclusion Golden bifid and smecta in the treatment of infantile diarrhea has a remarkable curative effect with no obvious adverse reaction, which is worthy of popularization in all levels of medical units at all levels.
KEYWORDS: golden bifid; smecta; infantile diarrhea

参考文献：
[1] 陈颖.金双岐联合思密达治疗小儿腹泻的疗效观察[J].医学临床研 究,2013,30(8):1565-1566.
[2] 卢薇.微生态制剂(金双岐)联合思密达治疗小儿腹泻的临床研究 [J].中国卫生产业,2014,11(33):3-4.
[3] 郑海燕.蒙脱石散联合金双岐治疗小儿腹泻50例临床疗效观察 [J].中国民族民间医药杂志,2014,23(19):64.
[4] 胡兴敏,刘书娅.金双歧联合思密达治疗小儿腹泻的疗效分析[J]. 中国医药指南,2016,14(15):75.
[5] 杨晓丹.思密达治疗小儿腹泻50例临床分析[J].中国医药指南,2016,14(15):100.
[6] 石立红,薛晓峰.思密达治疗小儿腹泻的临床疗效观察[J].临床医药文献杂志:电子版,2016,3(15):2913.
[7] 刘鑫.思密达治疗小儿腹泻的临床效果分析[J].现代诊断与治疗,2016,27(4):675-676.
[8] 化向霞.金双歧联合思密达治疗小儿腹泻临床价值探析[J].今日健康,2015,14(12):68.